DNA Motif Databases and Their Uses

Gary D. Stormo

doi:10.1002/0471250953.bi0215s51

DNA Motif Databases and Their Uses

Gary D. Stormo

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

Transcription factors (TFs) recognize and bind to specific DNA sequences. The specificity of a TF is usually represented as a position weight matrix (PWM). Several databases of DNA motifs exist and are used in biological research to address important biological questions. This overview describes PWMs and some of the most commonly used motif databases, as well as a few of their common applications.

Original language	English
Pages (from-to)	2.15.1-2.15.6
Journal	Current Protocols in Bioinformatics
Volume	51
Issue number	1
DOIs	https://doi.org/10.1002/0471250953.bi0215s51
State	Published - Sep 1 2015

Keywords

DNA motifs
binding site predictions
position weight matrices
transcription factors

Access to Document

10.1002/0471250953.bi0215s51

Cite this

@article{1332c103fb1248c49f54bd7bf5962e86,

title = "DNA Motif Databases and Their Uses",

abstract = "Transcription factors (TFs) recognize and bind to specific DNA sequences. The specificity of a TF is usually represented as a position weight matrix (PWM). Several databases of DNA motifs exist and are used in biological research to address important biological questions. This overview describes PWMs and some of the most commonly used motif databases, as well as a few of their common applications.",

keywords = "DNA motifs, binding site predictions, position weight matrices, transcription factors",

author = "Stormo, {Gary D.}",

note = "Publisher Copyright: {\textcopyright} 2015 John Wiley & Sons, Inc.",

year = "2015",

month = sep,

day = "1",

doi = "10.1002/0471250953.bi0215s51",

language = "English",

volume = "51",

pages = "2.15.1--2.15.6",

journal = "Current Protocols in Bioinformatics",

issn = "1934-3396",

number = "1",

}

TY - JOUR

T1 - DNA Motif Databases and Their Uses

AU - Stormo, Gary D.

PY - 2015/9/1

Y1 - 2015/9/1

N2 - Transcription factors (TFs) recognize and bind to specific DNA sequences. The specificity of a TF is usually represented as a position weight matrix (PWM). Several databases of DNA motifs exist and are used in biological research to address important biological questions. This overview describes PWMs and some of the most commonly used motif databases, as well as a few of their common applications.

AB - Transcription factors (TFs) recognize and bind to specific DNA sequences. The specificity of a TF is usually represented as a position weight matrix (PWM). Several databases of DNA motifs exist and are used in biological research to address important biological questions. This overview describes PWMs and some of the most commonly used motif databases, as well as a few of their common applications.

KW - DNA motifs

KW - binding site predictions

KW - position weight matrices

KW - transcription factors

UR - http://www.scopus.com/inward/record.url?scp=85005773732&partnerID=8YFLogxK

U2 - 10.1002/0471250953.bi0215s51

DO - 10.1002/0471250953.bi0215s51

M3 - Article

C2 - 26334922

AN - SCOPUS:85005773732

SN - 1934-3396

VL - 51

SP - 2.15.1-2.15.6

JO - Current Protocols in Bioinformatics

JF - Current Protocols in Bioinformatics

IS - 1

ER -

DNA Motif Databases and Their Uses

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this