TY - JOUR
T1 - Distinguishing normal and abnormal heart rate variability using graphical and non-linear analyses
AU - Stein, P. K.
AU - Hui, N.
AU - Domitrovich, P. P.
AU - Gottdiener, J.
AU - Rautaharju, P.
PY - 2004
Y1 - 2004
N2 - Abnormal HRV could confound risk stratification. Method: Hourly Poincaré and FFT plots examined in 270 tapes from the Cardiovascular Health Study. After 8 years, 63 subjects had died. Hourly short and longer-term detrended fractal scaling exponent and interbeat correlations were calculated. Hourly HRV was scored as normal (0), borderline (0.5) or abnormal (1) from plot appearance and HRV values. Scores were summed by subject and normalized to create an abnormality score (ABN,0-100%). Cox regression determined the relationship of ABN and mortality. Results: Increased ABN was associated with mortality, p=0.005. After adjustment for age (p=0.001) and gender (p=0.005), ABN remained associated with mortality (p=0.015). When ABN was dichotomized at 57%, HR and SDNN were not different, but higher ABN (N=67) had significantly increased short and intermediate-term HRV and mortality. Conclusion: Even with a relatively crude quantification method, abnormal rhythms were associated with both mortality and increased HRV.
AB - Abnormal HRV could confound risk stratification. Method: Hourly Poincaré and FFT plots examined in 270 tapes from the Cardiovascular Health Study. After 8 years, 63 subjects had died. Hourly short and longer-term detrended fractal scaling exponent and interbeat correlations were calculated. Hourly HRV was scored as normal (0), borderline (0.5) or abnormal (1) from plot appearance and HRV values. Scores were summed by subject and normalized to create an abnormality score (ABN,0-100%). Cox regression determined the relationship of ABN and mortality. Results: Increased ABN was associated with mortality, p=0.005. After adjustment for age (p=0.001) and gender (p=0.005), ABN remained associated with mortality (p=0.015). When ABN was dichotomized at 57%, HR and SDNN were not different, but higher ABN (N=67) had significantly increased short and intermediate-term HRV and mortality. Conclusion: Even with a relatively crude quantification method, abnormal rhythms were associated with both mortality and increased HRV.
UR - http://www.scopus.com/inward/record.url?scp=27744603517&partnerID=8YFLogxK
M3 - Conference article
AN - SCOPUS:27744603517
SN - 0276-6574
VL - 31
SP - 205
EP - 208
JO - Computers in Cardiology
JF - Computers in Cardiology
T2 - Computers in Cardiology 2004
Y2 - 19 September 2004 through 22 September 2004
ER -