TY - JOUR
T1 - Distinguishing features of acute Vogt-Koyanagi-Harada disease and acute central serous chorioretinopathy on optical coherence tomography angiography and en face optical coherence tomography imaging
AU - Aggarwal, Kanika
AU - Agarwal, Aniruddha
AU - Deokar, Ankit
AU - Mahajan, Sarakshi
AU - Singh, Ramandeep
AU - Bansal, Reema
AU - Sharma, Aman
AU - Dogra, Mangat R.
AU - Gupta, Vishali
AU - for the OCTA Study Group, the OCTA Study Group
N1 - Funding Information:
This work was partly supported by a grant from the Department of Science and Technology, India, for the development of Centre of Excellence at the Advanced Eye Centre, PGIMER, Chandigarh.
Publisher Copyright:
© 2017, The Author(s).
PY - 2017/12/1
Y1 - 2017/12/1
N2 - Background: The aim of this study is to determine the differences in optical coherence tomography angiography (OCTA) features of acute Vogt-Koyanagi-Harada disease (VKH) and acute central serous chorioretinopathy (CSC). Clinical and imaging data of patients with acute CSC and VKH in a tertiary-care institute were analyzed. Multimodal imaging including fluorescein angiography, indocyanine green angiography (ICGA), and enhanced-depth imaging OCT were performed. OCTA images were analyzed for alterations in retinochoroidal microvasculature. Results: Thirty-four eyes (24 patients; 10 with VKH and 14 with CSC) were included. OCTA en face images showed apparent areas of choriocapillaris flow void due to shadowing effect from overlying subretinal fluid and pigment epithelial detachment in CSC. However, eyes with VKH showed presence of true choriocapillaris flow void on OCTA that corresponded to choriocapillaris ischemia on ICGA. Conclusions: OCTA is a useful tool to assess choriocapillaris ischemia in VKH and is helpful to differentiate it from CSC in the acute stage.
AB - Background: The aim of this study is to determine the differences in optical coherence tomography angiography (OCTA) features of acute Vogt-Koyanagi-Harada disease (VKH) and acute central serous chorioretinopathy (CSC). Clinical and imaging data of patients with acute CSC and VKH in a tertiary-care institute were analyzed. Multimodal imaging including fluorescein angiography, indocyanine green angiography (ICGA), and enhanced-depth imaging OCT were performed. OCTA images were analyzed for alterations in retinochoroidal microvasculature. Results: Thirty-four eyes (24 patients; 10 with VKH and 14 with CSC) were included. OCTA en face images showed apparent areas of choriocapillaris flow void due to shadowing effect from overlying subretinal fluid and pigment epithelial detachment in CSC. However, eyes with VKH showed presence of true choriocapillaris flow void on OCTA that corresponded to choriocapillaris ischemia on ICGA. Conclusions: OCTA is a useful tool to assess choriocapillaris ischemia in VKH and is helpful to differentiate it from CSC in the acute stage.
KW - Central serous chorioretinopathy
KW - EDI-OCT
KW - Indocyanine green angiography
KW - Multimodal imaging
KW - Optical coherence tomography angiography
KW - Vogt-Koyanagi-Harada syndrome
UR - http://www.scopus.com/inward/record.url?scp=85009433478&partnerID=8YFLogxK
U2 - 10.1186/s12348-016-0122-z
DO - 10.1186/s12348-016-0122-z
M3 - Article
AN - SCOPUS:85009433478
SN - 1869-5760
VL - 7
JO - Journal of Ophthalmic Inflammation and Infection
JF - Journal of Ophthalmic Inflammation and Infection
IS - 1
M1 - 3
ER -