We analyzed bone marrow and blood from human immunodeficiency virus type 1 (HIV-1)-infected individuals and described the HIV-1 quasispecies in these cellular compartments. HIV-1 isolates from the bone marrow of thrombocytopenic patients contained distinct amino acids in the V3 loop and infected T-cell lines, implicating this virus in the development of thrombocytopenia.

Original languageEnglish
Pages (from-to)3497-3504
Number of pages8
JournalJournal of virology
Issue number4
StatePublished - Apr 1999


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