Distinct human immunodeficiency virus strains in the bone marrow are associated with the development of thrombocytopenia

Frosso Voulgaropoulou, Benjamin Tan, Marcelo Soares, Beatrice Hahn, Lee Ratner

Research output: Contribution to journalArticlepeer-review

14 Scopus citations

Abstract

We analyzed bone marrow and blood from human immunodeficiency virus type 1 (HIV-1)-infected individuals and described the HIV-1 quasispecies in these cellular compartments. HIV-1 isolates from the bone marrow of thrombocytopenic patients contained distinct amino acids in the V3 loop and infected T-cell lines, implicating this virus in the development of thrombocytopenia.

Original languageEnglish
Pages (from-to)3497-3504
Number of pages8
JournalJournal of virology
Volume73
Issue number4
DOIs
StatePublished - Apr 1999

Fingerprint

Dive into the research topics of 'Distinct human immunodeficiency virus strains in the bone marrow are associated with the development of thrombocytopenia'. Together they form a unique fingerprint.

Cite this