Dissociation of hunger and self-stimulation by trigeminal deafferentation in the rat

Mark F. Jacquin, Roger Harris, H. Philip Zeigler

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


Section of trigeminal orosensory or oromotor nerves reduces food intake and disrupts performance of a food-reinforced lever pressing response but increases the rate of an identical lever pressing response reinforced by electrical stimulation of the lateral hypothalamus. Our findings suggest that trigeminal orosensation plays a critical role in the neural control of hunger in the rat. These results also fail to support a response-oriented theory of intracranial self-stimulation where the latter is thought to involve selective facilitation of sensorimotor circuits underlying species-typical consummatory behavior.

Original languageEnglish
Pages (from-to)53-58
Number of pages6
JournalBrain Research
Issue number1
StatePublished - Jul 22 1982
Externally publishedYes


  • hunger
  • lateral hypothalamus
  • operant
  • rat
  • self-stimulation
  • sensorimotor
  • trigeminal deafferentation
  • trigeminal motor root


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