Dissociation of hunger and self-stimulation by trigeminal deafferentation in the rat

Mark F. Jacquin; Roger Harris; H. Philip Zeigler

doi:10.1016/0006-8993(82)90903-9

Dissociation of hunger and self-stimulation by trigeminal deafferentation in the rat

Mark F. Jacquin, Roger Harris, H. Philip Zeigler

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

Section of trigeminal orosensory or oromotor nerves reduces food intake and disrupts performance of a food-reinforced lever pressing response but increases the rate of an identical lever pressing response reinforced by electrical stimulation of the lateral hypothalamus. Our findings suggest that trigeminal orosensation plays a critical role in the neural control of hunger in the rat. These results also fail to support a response-oriented theory of intracranial self-stimulation where the latter is thought to involve selective facilitation of sensorimotor circuits underlying species-typical consummatory behavior.

Original language	English
Pages (from-to)	53-58
Number of pages	6
Journal	Brain Research
Volume	244
Issue number	1
DOIs	https://doi.org/10.1016/0006-8993(82)90903-9
State	Published - Jul 22 1982
Externally published	Yes

Keywords

hunger
lateral hypothalamus
operant
rat
self-stimulation
sensorimotor
trigeminal deafferentation
trigeminal motor root

Access to Document

10.1016/0006-8993(82)90903-9

Cite this

@article{258497c9da6045cd82ffd6781151263c,

title = "Dissociation of hunger and self-stimulation by trigeminal deafferentation in the rat",

abstract = "Section of trigeminal orosensory or oromotor nerves reduces food intake and disrupts performance of a food-reinforced lever pressing response but increases the rate of an identical lever pressing response reinforced by electrical stimulation of the lateral hypothalamus. Our findings suggest that trigeminal orosensation plays a critical role in the neural control of hunger in the rat. These results also fail to support a response-oriented theory of intracranial self-stimulation where the latter is thought to involve selective facilitation of sensorimotor circuits underlying species-typical consummatory behavior.",

keywords = "hunger, lateral hypothalamus, operant, rat, self-stimulation, sensorimotor, trigeminal deafferentation, trigeminal motor root",

author = "Jacquin, {Mark F.} and Roger Harris and Zeigler, {H. Philip}",

year = "1982",

month = jul,

day = "22",

doi = "10.1016/0006-8993(82)90903-9",

language = "English",

volume = "244",

pages = "53--58",

journal = "Brain Research",

issn = "0006-8993",

number = "1",

}

TY - JOUR

T1 - Dissociation of hunger and self-stimulation by trigeminal deafferentation in the rat

AU - Jacquin, Mark F.

AU - Harris, Roger

AU - Zeigler, H. Philip

PY - 1982/7/22

Y1 - 1982/7/22

N2 - Section of trigeminal orosensory or oromotor nerves reduces food intake and disrupts performance of a food-reinforced lever pressing response but increases the rate of an identical lever pressing response reinforced by electrical stimulation of the lateral hypothalamus. Our findings suggest that trigeminal orosensation plays a critical role in the neural control of hunger in the rat. These results also fail to support a response-oriented theory of intracranial self-stimulation where the latter is thought to involve selective facilitation of sensorimotor circuits underlying species-typical consummatory behavior.

AB - Section of trigeminal orosensory or oromotor nerves reduces food intake and disrupts performance of a food-reinforced lever pressing response but increases the rate of an identical lever pressing response reinforced by electrical stimulation of the lateral hypothalamus. Our findings suggest that trigeminal orosensation plays a critical role in the neural control of hunger in the rat. These results also fail to support a response-oriented theory of intracranial self-stimulation where the latter is thought to involve selective facilitation of sensorimotor circuits underlying species-typical consummatory behavior.

KW - hunger

KW - lateral hypothalamus

KW - operant

KW - rat

KW - self-stimulation

KW - sensorimotor

KW - trigeminal deafferentation

KW - trigeminal motor root

UR - http://www.scopus.com/inward/record.url?scp=0019958551&partnerID=8YFLogxK

U2 - 10.1016/0006-8993(82)90903-9

DO - 10.1016/0006-8993(82)90903-9

M3 - Article

C2 - 7116169

AN - SCOPUS:0019958551

SN - 0006-8993

VL - 244

SP - 53

EP - 58

JO - Brain Research

JF - Brain Research

IS - 1

ER -

Dissociation of hunger and self-stimulation by trigeminal deafferentation in the rat

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this