TY - JOUR
T1 - Disciform keratitis
T2 - A case of herpes zoster sine herpete
AU - Silverstein, B. E.
AU - Chandler, D.
AU - Neger, R.
AU - Margolis, T. P.
N1 - Funding Information:
The Francis I. Proctor Foundation and Department of Ophthalmology, University of California, San Francisco Medical Center. Supported by a Research to Prevent Blindness Law Wasserman Merit Award (T.P.M.), a grant from the University-wide AIDS Research Program, Oakland, California (T.P.M.), and National Institutes of Health grant no. EY02162 (core grant).
PY - 1997
Y1 - 1997
N2 - PURPOSE: To describe a case of disciform keratitis in a patient with acquired immunodeficiency syndrome (AIDS) in which varicella-zoster virus was the causative agent. METHOD: Case report. Polymerase chain reaction-based assays for varicella-zoster virus, cytomegalovirus, and herpes simplex virus were used to analyze an aqueous aspirate. RESULTS: We examined a 41-year-old man with AIDS but without a history of varicella-zoster virus dermatitis who had disciform corneal edema in his left eye. Varicella-zoster virus was detected by a polymerase chain reaction-based assay in the aqueous of the left eye; however, neither cytomegalovirus nor herpes simplex virus DNA were detected by polymerase chain reaction-based assays. The corneal edema slowly resolved while the patient was treated with famciclovir. CONCLUSION: Varicella-zoster virus may cause disciform keratitis without a preceding skin eruption.
AB - PURPOSE: To describe a case of disciform keratitis in a patient with acquired immunodeficiency syndrome (AIDS) in which varicella-zoster virus was the causative agent. METHOD: Case report. Polymerase chain reaction-based assays for varicella-zoster virus, cytomegalovirus, and herpes simplex virus were used to analyze an aqueous aspirate. RESULTS: We examined a 41-year-old man with AIDS but without a history of varicella-zoster virus dermatitis who had disciform corneal edema in his left eye. Varicella-zoster virus was detected by a polymerase chain reaction-based assay in the aqueous of the left eye; however, neither cytomegalovirus nor herpes simplex virus DNA were detected by polymerase chain reaction-based assays. The corneal edema slowly resolved while the patient was treated with famciclovir. CONCLUSION: Varicella-zoster virus may cause disciform keratitis without a preceding skin eruption.
UR - http://www.scopus.com/inward/record.url?scp=0031013598&partnerID=8YFLogxK
U2 - 10.1016/S0002-9394(14)71044-X
DO - 10.1016/S0002-9394(14)71044-X
M3 - Article
C2 - 9186133
AN - SCOPUS:0031013598
SN - 0002-9394
VL - 123
SP - 254
EP - 255
JO - American journal of ophthalmology
JF - American journal of ophthalmology
IS - 2
ER -