Direct chromosome preparations from chorionic villi: A method for obtaining extended chromosomes and recognizing mosaicism confined to the placenta

S. W. Cheung; J. P. Crane; M. Kyine; M. Y. Cui

doi:10.1159/000132441

Direct chromosome preparations from chorionic villi: A method for obtaining extended chromosomes and recognizing mosaicism confined to the placenta

S. W. Cheung
, J. P. Crane
, M. Kyine
, M. Y. Cui

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

A modified technique is described for obtaining extended metaphase chromosomes (600 bands) from direct preparations of chorionic villi, allowing rapid detection of subtle structural aberrations with minimal risk of maternal-cell contamination. Analysis of multiple individually processed villus fragments may be helpful in recognizing mosaicism confined to chorionic villi.

Original language	English
Pages (from-to)	118-120
Number of pages	3
Journal	Cytogenetics and cell genetics
Volume	45
Issue number	2
DOIs	https://doi.org/10.1159/000132441
State	Published - 1987

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title = "Direct chromosome preparations from chorionic villi: A method for obtaining extended chromosomes and recognizing mosaicism confined to the placenta",

abstract = "A modified technique is described for obtaining extended metaphase chromosomes (600 bands) from direct preparations of chorionic villi, allowing rapid detection of subtle structural aberrations with minimal risk of maternal-cell contamination. Analysis of multiple individually processed villus fragments may be helpful in recognizing mosaicism confined to chorionic villi.",

author = "Cheung, \{S. W.\} and Crane, \{J. P.\} and M. Kyine and Cui, \{M. Y.\}",

year = "1987",

doi = "10.1159/000132441",

language = "English",

volume = "45",

pages = "118--120",

journal = "Cytogenetics and cell genetics",

issn = "0301-0171",

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TY - JOUR

T1 - Direct chromosome preparations from chorionic villi

T2 - A method for obtaining extended chromosomes and recognizing mosaicism confined to the placenta

AU - Cheung, S. W.

AU - Crane, J. P.

AU - Kyine, M.

AU - Cui, M. Y.

PY - 1987

Y1 - 1987

N2 - A modified technique is described for obtaining extended metaphase chromosomes (600 bands) from direct preparations of chorionic villi, allowing rapid detection of subtle structural aberrations with minimal risk of maternal-cell contamination. Analysis of multiple individually processed villus fragments may be helpful in recognizing mosaicism confined to chorionic villi.

AB - A modified technique is described for obtaining extended metaphase chromosomes (600 bands) from direct preparations of chorionic villi, allowing rapid detection of subtle structural aberrations with minimal risk of maternal-cell contamination. Analysis of multiple individually processed villus fragments may be helpful in recognizing mosaicism confined to chorionic villi.

UR - https://www.scopus.com/pages/publications/0023217152

U2 - 10.1159/000132441

DO - 10.1159/000132441

M3 - Article

C2 - 3622010

AN - SCOPUS:0023217152

SN - 0301-0171

VL - 45

SP - 118

EP - 120

JO - Cytogenetics and cell genetics

JF - Cytogenetics and cell genetics

IS - 2

ER -

Direct chromosome preparations from chorionic villi: A method for obtaining extended chromosomes and recognizing mosaicism confined to the placenta

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