Dimethyl (±)-(1S*,2R*,3S*)-[3-phenyl-1-(N-phenylcarbamoyloxy)-2, 3-epoxypropyl]-phosphonate

  • Todd Boehlow
  • , Antonette De La Cruz
  • , Nigam P. Rath
  • , Christopher D. Spilling

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

The crystal structure of the racemic title compound, C18H20NO6P (m.p. 428-431 K), has been determined by X-ray diffraction. The title compound consists of a tetrahedral P atom bonded to two methoxy groups, and an alkyl chain. The alkyl chain is substituted at position 1 with a carbamate and with an epoxide at positions 2 and 3. The relative configuration of the 1-carbamate and 2,3-epoxide substituents was confirmed as anti (1S,2R,3S). The crystal structure contains an enantiomeric pair with two intermolecular hydrogen bonds in a 14-membered ring. The hydrogen bonds are formed between the P=O of one enantiomer and the N-H of the other.

Original languageEnglish
Pages (from-to)1947-1949
Number of pages3
JournalActa Crystallographica Section C: Crystal Structure Communications
Volume53
Issue number11
StatePublished - Nov 15 1997

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