TY - JOUR
T1 - Digital tissue and what it may reveal about the brain
AU - Morgan, Josh L.
AU - Lichtman, Jeff W.
N1 - Funding Information:
This work was supported by NIH/NINDS (High Resolution Connectomics of Mammalian Neural Circuits, TR01 1R01NS076467 and 1U01NS090449-01) and the NIMH Silvio Conte Center (1P50MH094271), IARPA via DoI/IBC (D16PC00002), MURI Army Research Office (contract number W911NF1210594 and IIS-1447786).
Publisher Copyright:
© 2017 Morgan et al.
PY - 2017/10/30
Y1 - 2017/10/30
N2 - Imaging as a means of scientific data storage has evolved rapidly over the past century from hand drawings, to photography, to digital images. Only recently can sufficiently large datasets be acquired, stored, and processed such that tissue digitization can actually reveal more than direct observation of tissue. One field where this transformation is occurring is connectomics: the mapping of neural connections in large volumes of digitized brain tissue.
AB - Imaging as a means of scientific data storage has evolved rapidly over the past century from hand drawings, to photography, to digital images. Only recently can sufficiently large datasets be acquired, stored, and processed such that tissue digitization can actually reveal more than direct observation of tissue. One field where this transformation is occurring is connectomics: the mapping of neural connections in large volumes of digitized brain tissue.
UR - http://www.scopus.com/inward/record.url?scp=85032584004&partnerID=8YFLogxK
U2 - 10.1186/s12915-017-0436-9
DO - 10.1186/s12915-017-0436-9
M3 - Review article
C2 - 29084528
AN - SCOPUS:85032584004
SN - 1741-7007
VL - 15
JO - BMC Biology
JF - BMC Biology
IS - 1
M1 - 101
ER -