Diffusion tensor imaging of mouse brain stem and cervical spinal cord

Joong Hee Kim, Justin Haldar, Zhi Pei Liang, Sheng Kwei Song

Research output: Contribution to journalArticle

12 Scopus citations

Abstract

In vivo diffusion tensor imaging measurements of the mouse brain stem and cervical spinal cord are presented. Utilizing actively decoupled transmit/receive coils, high resolution diffusion images (117 μm × 59 μm × 500 μm) were acquired at 4.7 T within an hour. Both brain stem and cervical spine displayed clear gray-white matter contrast. The cervical spinal cord white matter showed similar tissue characteristics as seen in the thoracic cord. The coherent fiber orientation in the white matter was observed in both the brain stem and the cervical spinal cord. The results may serve as a reference for future inter-lab comparison in mouse brain stem and cervical spine diffusion measurements.

Original languageEnglish
Pages (from-to)186-191
Number of pages6
JournalJournal of Neuroscience Methods
Volume176
Issue number2
DOIs
StatePublished - Jan 30 2009

Keywords

  • Axial and radial diffusivity
  • Brain stem
  • Cervical spinal cord
  • Diffusion anisotropy
  • Diffusion tensor imaging
  • Mice

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