Differential Regulation of Bladder Pain and Voiding Function by Sensory Afferent Populations Revealed by Selective Optogenetic Activation

Keyphrases

• Differential Regulation 100%
• Optogenetic Stimulation 100%
• Voiding Function 100%
• Dorsal Horn 100%
• Bladder Filling 100%
• Sensory Afferents 100%
• Bladder Pain 100%
• High Amplitudes 100%
• Transgenic Lines 66%
• Bladder Function 66%
• Low Amplitude 66%
• Channelrhodopsin-2 (ChR2) 66%
• Nociceptor 66%
• Bladder 33%
• Depolarization 33%
• Dorsal Root Ganglion Neurons 33%
• Spinal Cord 33%
• Afferent Neurons 33%
• Fusion Protein 33%
• Reflex 33%
• Distinct Population Segment 33%
• Excitatory Synaptic Transmission 33%
• Transient Receptor Potential Vanilloid 1 (TRPV1) 33%
• Primary Sensory Neurons 33%
• Mechanosensitive 33%
• Overactivity 33%
• Sensory Neurons 33%
• Nav1.8 33%
• Bladder Contraction 33%
• Visceromotor Response 33%
• Bladder Sensation 33%
• Distension 33%
• Fiber Density 33%
• Photostimulation 33%
• Spinal Circuits 33%
• Physiological Differences 33%
• Lamina I 33%
• Lamina X 33%
• Bladder Distension 33%
• Pathological State 33%
• Low Threshold Mechanoreceptors 33%
• Peripheral Afferents 33%

Neuroscience

• Sensory Neuron 100%
• Optogenetics 100%
• Nociceptor 100%
• In Vivo 50%
• Dorsal Root Ganglion 50%
• Afferent Neurons 50%
• Synaptic Transmission 50%
• Channelrhodopsin 50%
• TRPV1 50%
• Chimeric Protein 50%
• Mechanoreceptor 50%
• Spinal Cord 50%
• Spinal Circuit 50%