Diagnostic yield of targeted next generation sequencing in various cancer types: An information-theoretic approach

Keyphrases

• Tumor 100%
• Cancer Types 100%
• Metagenomic Next-generation Sequencing (mNGS) 100%
• Information Theory 100%
• Diagnostic Yield 100%
• Tumor Subtype 66%
• Genotype 66%
• NGS Testing 66%
• Clinical Significance 33%
• PIK3CA 33%
• Pancreatic Cancer 33%
• Colorectal Cancer 33%
• Laboratory Testing 33%
• Diagnostic Test 33%
• Isocitrate Dehydrogenase 1 (IDH1) 33%
• Lung Cancer 33%
• Surgical Pathology 33%
• Information Content 33%
• Sarcoma 33%
• Exon 33%
• Novel Measure 33%
• High-grade Glioma 33%
• Clinical Sequencing 33%
• Shannon Entropy 33%
• Pten 33%
• Egfr 33%
• Janus Kinase 2 (JAK2) 33%
• Lower Average 33%
• B-Raf 33%
• Mutational Profile 33%
• Actionable mutations 33%
• Pathology Examination 33%
• Targeted NGS 33%
• Average Information 33%
• Actionable Variants 33%

Biochemistry, Genetics and Molecular Biology

• Next Generation Sequencing 100%
• Entropy 66%
• Epidermal Growth Factor Receptor 16%
• Exon 16%
• KRAS 16%
• Laboratory Test 16%
• Genotyping 16%
• IDH1 16%
• Janus Kinase 16%