TY - JOUR
T1 - Diagnosis of concurrent pulmonary tuberculosis and tuberculous otitis media confirmed by Xpert MTB/RIF in the United States
AU - Tompkins, Kathleen M.
AU - Reimers, Melissa A.
AU - White, Becky L.
AU - Herce, Michael E.
N1 - Publisher Copyright:
© 2016 Wolters Kluwer Health, Inc.
PY - 2016/5/1
Y1 - 2016/5/1
N2 - Tuberculosis (TB) remains an important cause of infectious morbidity in the United States, necessitating timely and accurate diagnosis. We report a case of concurrent pulmonary and extrapulmonary TB presenting as tuberculous otitis media in a hospitalized US patient admitted with cough, night sweats, and unilateral purulent otorrhea. Diagnosis was made by smear microscopy and rapidly confirmed by Xpert MTB/RIF - a novel, automated nucleic acid amplification test for the rapid detection of drug-susceptible and drug-resistant TB. This case adds to the growing body of evidence validating Xpert MTB/RIF as an effective tool for the rapid diagnosis of extrapulmonary TB, even in low-TB prevalence settings such as the United States, when testing is performed on nonrespiratory specimens.
AB - Tuberculosis (TB) remains an important cause of infectious morbidity in the United States, necessitating timely and accurate diagnosis. We report a case of concurrent pulmonary and extrapulmonary TB presenting as tuberculous otitis media in a hospitalized US patient admitted with cough, night sweats, and unilateral purulent otorrhea. Diagnosis was made by smear microscopy and rapidly confirmed by Xpert MTB/RIF - a novel, automated nucleic acid amplification test for the rapid detection of drug-susceptible and drug-resistant TB. This case adds to the growing body of evidence validating Xpert MTB/RIF as an effective tool for the rapid diagnosis of extrapulmonary TB, even in low-TB prevalence settings such as the United States, when testing is performed on nonrespiratory specimens.
KW - Xpert
KW - chronic otitis media
KW - extrapulmonary tuberculosis
KW - nucleic acid amplification test
KW - otorrhea
UR - http://www.scopus.com/inward/record.url?scp=84944345068&partnerID=8YFLogxK
U2 - 10.1097/IPC.0000000000000333
DO - 10.1097/IPC.0000000000000333
M3 - Article
C2 - 27346926
AN - SCOPUS:84944345068
SN - 1056-9103
VL - 24
SP - 180
EP - 182
JO - Infectious Diseases in Clinical Practice
JF - Infectious Diseases in Clinical Practice
IS - 3
ER -