Tuberculosis (TB) remains an important cause of infectious morbidity in the United States, necessitating timely and accurate diagnosis. We report a case of concurrent pulmonary and extrapulmonary TB presenting as tuberculous otitis media in a hospitalized US patient admitted with cough, night sweats, and unilateral purulent otorrhea. Diagnosis was made by smear microscopy and rapidly confirmed by Xpert MTB/RIF - a novel, automated nucleic acid amplification test for the rapid detection of drug-susceptible and drug-resistant TB. This case adds to the growing body of evidence validating Xpert MTB/RIF as an effective tool for the rapid diagnosis of extrapulmonary TB, even in low-TB prevalence settings such as the United States, when testing is performed on nonrespiratory specimens.
- chronic otitis media
- extrapulmonary tuberculosis
- nucleic acid amplification test