Diabetes

Raymond E. Bourey, Meenakshi K. Kaw, Sumona Ghosh Lester, Simona S. Ghanem, Sonia M. Najjar

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

2 Scopus citations

Abstract

Diabetes mellitus is a disease diagnosed by fasting hyperglycemia that results from defects in insulin secretion, insulin action, or both. Impact of diabetes mellitus on the economy of the United States is overwhelming as an estimated 25.8 million people or 8.3% of the population have diabetes mellitus. This incidence of the disease has doubled since 1980. As diabetes is the leading cause of new renal failure, blindness, and nontraumatic lower-limb amputations, as well as a major contributor to heart disease, stroke, and complications of pregnancy, it is not surprising that costs were estimated in 2007 at $174 billion. The adverse effects of the twin epidemics of obesity and diabetes are expected to rise, unless we develop effective therapeutic and preventive strategies. This chapter reviews the development and pathophysiology of diabetes and discusses therapeutic and preventive value of diet and exercise against this disease.

Original languageEnglish
Title of host publicationDiet, Exercise, and Chronic Disease
Subtitle of host publicationThe Biological Basis of Prevention
PublisherCRC Press
Pages101-132
Number of pages32
ISBN (Electronic)9781439850299
ISBN (Print)9781439850282
DOIs
StatePublished - Jan 1 2014

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