Abstract
Diabetes mellitus is a disease diagnosed by fasting hyperglycemia that results from defects in insulin secretion, insulin action, or both. Impact of diabetes mellitus on the economy of the United States is overwhelming as an estimated 25.8 million people or 8.3% of the population have diabetes mellitus. This incidence of the disease has doubled since 1980. As diabetes is the leading cause of new renal failure, blindness, and nontraumatic lower-limb amputations, as well as a major contributor to heart disease, stroke, and complications of pregnancy, it is not surprising that costs were estimated in 2007 at $174 billion. The adverse effects of the twin epidemics of obesity and diabetes are expected to rise, unless we develop effective therapeutic and preventive strategies. This chapter reviews the development and pathophysiology of diabetes and discusses therapeutic and preventive value of diet and exercise against this disease.
Original language | English |
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Title of host publication | Diet, Exercise, and Chronic Disease |
Subtitle of host publication | The Biological Basis of Prevention |
Publisher | CRC Press |
Pages | 101-132 |
Number of pages | 32 |
ISBN (Electronic) | 9781439850299 |
ISBN (Print) | 9781439850282 |
DOIs | |
State | Published - Jan 1 2014 |