DGIdb: Mining the druggable genome

Malachi Griffith, Obi L. Griffith, Adam C. Coffman, James V. Weible, Josh F. Mcmichael, Nicholas C. Spies, James Koval, Indraniel Das, Matthew B. Callaway, James M. Eldred, Christopher A. Miller, Janakiraman Subramanian, Ramaswamy Govindan, Runjun D. Kumar, Ron Bose, Li Ding, Jason R. Walker, David E. Larson, David J. Dooling, Scott M. SmithTimothy J. Ley, Elaine R. Mardis, Richard K. Wilson

Research output: Contribution to journalArticle

242 Scopus citations

Abstract

The Drug-Gene Interaction database (DGIdb) mines existing resources that generate hypotheses about how mutated genes might be targeted therapeutically or prioritized for drug development. It provides an interface for searching lists of genes against a compendium of drug-gene interactions and potentially 'druggable' genes. DGIdb can be accessed at http://dgidb.org/.

Original languageEnglish
Pages (from-to)1209-1210
Number of pages2
JournalNature Methods
Volume10
Issue number12
DOIs
StatePublished - Dec 1 2013

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    Griffith, M., Griffith, O. L., Coffman, A. C., Weible, J. V., Mcmichael, J. F., Spies, N. C., Koval, J., Das, I., Callaway, M. B., Eldred, J. M., Miller, C. A., Subramanian, J., Govindan, R., Kumar, R. D., Bose, R., Ding, L., Walker, J. R., Larson, D. E., Dooling, D. J., ... Wilson, R. K. (2013). DGIdb: Mining the druggable genome. Nature Methods, 10(12), 1209-1210. https://doi.org/10.1038/nmeth.2689