Abstract
We present a robot that enables high-content studies of alert adult Drosophila by combining operations including gentle picking; translations and rotations; characterizations of fly phenotypes and behaviors; microdissection; or release. To illustrate, we assessed fly morphology, tracked odor-evoked locomotion, sorted flies by sex, and dissected the cuticle to image neural activity. The robot's tireless capacity for precise manipulations enables a scalable platform for screening flies' complex attributes and behavioral patterns.
| Original language | English |
|---|---|
| Pages (from-to) | 657-660 |
| Number of pages | 4 |
| Journal | Nature Methods |
| Volume | 12 |
| Issue number | 7 |
| DOIs | |
| State | Published - Jun 30 2015 |