Developmental transformation of dendritic arbors in mouse whisker thalamus

Kimberly E. Brown; Josephus J.A. Arends; Scott P. Wasserstrom; Judith B. Zantua; Mark F. Jacquin; Thomas A. Woolsey

doi:10.1016/0165-3806(94)00210-Q

Developmental transformation of dendritic arbors in mouse whisker thalamus

Kimberly E. Brown, Josephus J.A. Arends, Scott P. Wasserstrom, Judith B. Zantua, Mark F. Jacquin, Thomas A. Woolsey

Department of Neurology

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

Neurons in slices though the somatosensory thalamus of postnatal day 6 and adult mice were injected with Lucifer yellow. Dendritic arbors on postnatal day 6 are confined to single barreloids (single whisker representations); in adults they are seven times longer, extending beyond their barreloid to adjacent barreloids. The postnatal transformation of dendritic arbors by total process growth and extension to adjacent barreloids suggests a developmental change in the role of these cells from instructing whisker pattern formation to integrating sensory information from more than one whisker.

Original language	English
Pages (from-to)	335-339
Number of pages	5
Journal	Developmental Brain Research
Volume	86
Issue number	1-2
DOIs	https://doi.org/10.1016/0165-3806(94)00210-Q
State	Published - May 26 1995

Keywords

Barrel
Barreloid
Pattern formation
Thalamocortical relay cell

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10.1016/0165-3806(94)00210-Q

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title = "Developmental transformation of dendritic arbors in mouse whisker thalamus",

abstract = "Neurons in slices though the somatosensory thalamus of postnatal day 6 and adult mice were injected with Lucifer yellow. Dendritic arbors on postnatal day 6 are confined to single barreloids (single whisker representations); in adults they are seven times longer, extending beyond their barreloid to adjacent barreloids. The postnatal transformation of dendritic arbors by total process growth and extension to adjacent barreloids suggests a developmental change in the role of these cells from instructing whisker pattern formation to integrating sensory information from more than one whisker.",

keywords = "Barrel, Barreloid, Pattern formation, Thalamocortical relay cell",

author = "Brown, {Kimberly E.} and Arends, {Josephus J.A.} and Wasserstrom, {Scott P.} and Zantua, {Judith B.} and Jacquin, {Mark F.} and Woolsey, {Thomas A.}",

note = "Funding Information: This paper is dedicated to the memory of the late Hendrik van der Loos. We thank Jane Linglebscb, M.D. for initial work and Jon Christensen and Georgian Witt for technical help. Supported by NIH Grants DE 07734, DE 07662, and NS 17763 and by the Spastic Paralysis Foundation of the llliiois Eastern-Iowa District of the Kiwanis International and The McDonnell Center for Studies of Higher Brain Function.",

year = "1995",

month = may,

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doi = "10.1016/0165-3806(94)00210-Q",

language = "English",

volume = "86",

pages = "335--339",

journal = "Developmental Brain Research",

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T1 - Developmental transformation of dendritic arbors in mouse whisker thalamus

AU - Brown, Kimberly E.

AU - Arends, Josephus J.A.

AU - Wasserstrom, Scott P.

AU - Zantua, Judith B.

AU - Jacquin, Mark F.

AU - Woolsey, Thomas A.

N1 - Funding Information: This paper is dedicated to the memory of the late Hendrik van der Loos. We thank Jane Linglebscb, M.D. for initial work and Jon Christensen and Georgian Witt for technical help. Supported by NIH Grants DE 07734, DE 07662, and NS 17763 and by the Spastic Paralysis Foundation of the llliiois Eastern-Iowa District of the Kiwanis International and The McDonnell Center for Studies of Higher Brain Function.

PY - 1995/5/26

Y1 - 1995/5/26

N2 - Neurons in slices though the somatosensory thalamus of postnatal day 6 and adult mice were injected with Lucifer yellow. Dendritic arbors on postnatal day 6 are confined to single barreloids (single whisker representations); in adults they are seven times longer, extending beyond their barreloid to adjacent barreloids. The postnatal transformation of dendritic arbors by total process growth and extension to adjacent barreloids suggests a developmental change in the role of these cells from instructing whisker pattern formation to integrating sensory information from more than one whisker.

AB - Neurons in slices though the somatosensory thalamus of postnatal day 6 and adult mice were injected with Lucifer yellow. Dendritic arbors on postnatal day 6 are confined to single barreloids (single whisker representations); in adults they are seven times longer, extending beyond their barreloid to adjacent barreloids. The postnatal transformation of dendritic arbors by total process growth and extension to adjacent barreloids suggests a developmental change in the role of these cells from instructing whisker pattern formation to integrating sensory information from more than one whisker.

KW - Barrel

KW - Barreloid

KW - Pattern formation

KW - Thalamocortical relay cell

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U2 - 10.1016/0165-3806(94)00210-Q

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SN - 0165-3806

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SP - 335

EP - 339

JO - Developmental Brain Research

JF - Developmental Brain Research

IS - 1-2

ER -

Developmental transformation of dendritic arbors in mouse whisker thalamus

Abstract

Keywords

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