TY - JOUR
T1 - Developmental and molecular biology of annelid regeneration
T2 - a comparative review of recent studies
AU - Özpolat, B. Duygu
AU - Bely, Alexandra E.
N1 - Publisher Copyright:
© 2016 Elsevier Ltd
PY - 2016/10/1
Y1 - 2016/10/1
N2 - Studies of annelid regeneration have greatly increased in frequency in recent years, providing new insights into the developmental basis and evolution of regeneration. In this review, we summarize recent findings related to regeneration in annelids, focusing on molecular and developmental studies of epimorphic (blastema-based) regeneration, morphallactic (tissue-remodeling based) regeneration, and development and regeneration of putative stem cells of the posterior growth zone and germline. Regeneration is being investigated in a broad range of annelids spanning the phylum, and comparing findings among species reveals both widely conserved features that may be ancestral for the phylum as well as features that are variable across the group.
AB - Studies of annelid regeneration have greatly increased in frequency in recent years, providing new insights into the developmental basis and evolution of regeneration. In this review, we summarize recent findings related to regeneration in annelids, focusing on molecular and developmental studies of epimorphic (blastema-based) regeneration, morphallactic (tissue-remodeling based) regeneration, and development and regeneration of putative stem cells of the posterior growth zone and germline. Regeneration is being investigated in a broad range of annelids spanning the phylum, and comparing findings among species reveals both widely conserved features that may be ancestral for the phylum as well as features that are variable across the group.
UR - http://www.scopus.com/inward/record.url?scp=84982840712&partnerID=8YFLogxK
U2 - 10.1016/j.gde.2016.07.010
DO - 10.1016/j.gde.2016.07.010
M3 - Review article
C2 - 27505269
AN - SCOPUS:84982840712
SN - 0959-437X
VL - 40
SP - 144
EP - 153
JO - Current Opinion in Genetics and Development
JF - Current Opinion in Genetics and Development
ER -