Development of sarcoidosis during treatment for chronic hepatitis c with pegylated interferon α-2a and ribavirin: Case report and literature review

Bruno Cacopardo; Marilia Rita Pinzone; Giuseppe Nunnari

Development of sarcoidosis during treatment for chronic hepatitis c with pegylated interferon α-2a and ribavirin: Case report and literature review

Bruno Cacopardo
, Marilia Rita Pinzone
, Giuseppe Nunnari

Division of Infectious Diseases

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Sarcoidosis is a chronic inflammatory multisystem disease of unknown aetiology. IFN-α is an immunomodulatory cytokine, currently used with ribavirin in the treatment of chronic hepatitis C infection. Due to its effects on the immune system, IFN-α may lead to the induction or exacerbation of autoimmune diseases, such as systemic lupus erythematosus, rheumatoid arthritis and sarcoidosis. We report on a 37-year-old man, presenting with sarcoidosis during a six-month course of PEG-IFN α-2a and ribavirin for chronic hepatitis C virus genotype 3 infection.

Original language	English
Pages (from-to)	40-44
Number of pages	5
Journal	Infezioni in Medicina
Volume	21
Issue number	1
State	Published - Mar 2013

Keywords

HCV
Interferon
Sarcoidosis

Cite this

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title = "Development of sarcoidosis during treatment for chronic hepatitis c with pegylated interferon α-2a and ribavirin: Case report and literature review",

abstract = "Sarcoidosis is a chronic inflammatory multisystem disease of unknown aetiology. IFN-α is an immunomodulatory cytokine, currently used with ribavirin in the treatment of chronic hepatitis C infection. Due to its effects on the immune system, IFN-α may lead to the induction or exacerbation of autoimmune diseases, such as systemic lupus erythematosus, rheumatoid arthritis and sarcoidosis. We report on a 37-year-old man, presenting with sarcoidosis during a six-month course of PEG-IFN α-2a and ribavirin for chronic hepatitis C virus genotype 3 infection.",

keywords = "HCV, Interferon, Sarcoidosis",

author = "Bruno Cacopardo and Pinzone, \{Marilia Rita\} and Giuseppe Nunnari",

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T2 - Case report and literature review

AU - Cacopardo, Bruno

AU - Pinzone, Marilia Rita

AU - Nunnari, Giuseppe

PY - 2013/3

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N2 - Sarcoidosis is a chronic inflammatory multisystem disease of unknown aetiology. IFN-α is an immunomodulatory cytokine, currently used with ribavirin in the treatment of chronic hepatitis C infection. Due to its effects on the immune system, IFN-α may lead to the induction or exacerbation of autoimmune diseases, such as systemic lupus erythematosus, rheumatoid arthritis and sarcoidosis. We report on a 37-year-old man, presenting with sarcoidosis during a six-month course of PEG-IFN α-2a and ribavirin for chronic hepatitis C virus genotype 3 infection.

AB - Sarcoidosis is a chronic inflammatory multisystem disease of unknown aetiology. IFN-α is an immunomodulatory cytokine, currently used with ribavirin in the treatment of chronic hepatitis C infection. Due to its effects on the immune system, IFN-α may lead to the induction or exacerbation of autoimmune diseases, such as systemic lupus erythematosus, rheumatoid arthritis and sarcoidosis. We report on a 37-year-old man, presenting with sarcoidosis during a six-month course of PEG-IFN α-2a and ribavirin for chronic hepatitis C virus genotype 3 infection.

KW - HCV

KW - Interferon

KW - Sarcoidosis

UR - https://www.scopus.com/pages/publications/84875615040

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AN - SCOPUS:84875615040

SN - 1124-9390

VL - 21

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JO - Infezioni in Medicina

JF - Infezioni in Medicina

IS - 1

ER -

Development of sarcoidosis during treatment for chronic hepatitis c with pegylated interferon α-2a and ribavirin: Case report and literature review

Abstract

Keywords

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