TY - JOUR
T1 - Development of sarcoidosis during treatment for chronic hepatitis c with pegylated interferon α-2a and ribavirin
T2 - Case report and literature review
AU - Cacopardo, Bruno
AU - Pinzone, Marilia Rita
AU - Nunnari, Giuseppe
PY - 2013/3
Y1 - 2013/3
N2 - Sarcoidosis is a chronic inflammatory multisystem disease of unknown aetiology. IFN-α is an immunomodulatory cytokine, currently used with ribavirin in the treatment of chronic hepatitis C infection. Due to its effects on the immune system, IFN-α may lead to the induction or exacerbation of autoimmune diseases, such as systemic lupus erythematosus, rheumatoid arthritis and sarcoidosis. We report on a 37-year-old man, presenting with sarcoidosis during a six-month course of PEG-IFN α-2a and ribavirin for chronic hepatitis C virus genotype 3 infection.
AB - Sarcoidosis is a chronic inflammatory multisystem disease of unknown aetiology. IFN-α is an immunomodulatory cytokine, currently used with ribavirin in the treatment of chronic hepatitis C infection. Due to its effects on the immune system, IFN-α may lead to the induction or exacerbation of autoimmune diseases, such as systemic lupus erythematosus, rheumatoid arthritis and sarcoidosis. We report on a 37-year-old man, presenting with sarcoidosis during a six-month course of PEG-IFN α-2a and ribavirin for chronic hepatitis C virus genotype 3 infection.
KW - HCV
KW - Interferon
KW - Sarcoidosis
UR - http://www.scopus.com/inward/record.url?scp=84875615040&partnerID=8YFLogxK
M3 - Article
C2 - 23524900
AN - SCOPUS:84875615040
SN - 1124-9390
VL - 21
SP - 40
EP - 44
JO - Infezioni in Medicina
JF - Infezioni in Medicina
IS - 1
ER -