TY - JOUR
T1 - Development of a multi-institutional clinical research consortium for pediatric surgery
AU - MidWest Pediatric Surgery Consortium (MWPSC)
AU - Hirschl, Ronald B.
AU - Minneci, Peter
AU - Gadepalli, Samir
AU - Saito, Jacqueline M.
AU - Askegard-Giesmann, Johanna
AU - Deans, Katherine
AU - Downard, Cynthia
AU - Fallat, Mary
AU - Finnell, Maria
AU - Helmrath, Michael
AU - Kabre, Rashmi
AU - Lal, David
AU - Leys, Charles
AU - Mak, Grace
AU - Ostlie, Daniel
AU - Rescorla, Fred
AU - Sato, Thomas
AU - St. Peter, Shawn
AU - von Allmen, Daniel
AU - Warner, Brad
N1 - Publisher Copyright:
© 2016 Elsevier Inc.
PY - 2017/7
Y1 - 2017/7
N2 - Background Multicenter clinical research studies in pediatric surgery have been largely limited to relatively small case-series and retrospective reviews because of the rarity of many of the diseases we treat and difficulty coordinating and executing multi-institutional studies. Creation of a collaborative research network can provide the needed patient population and infrastructure to perform high quality multi-institutional studies. Methods In 2013, eleven academic pediatric surgery centers within the United States formed a research consortium to develop and conduct multicenter clinical research projects to advance the practice of pediatric surgery. Results We present our process for creating, developing, and maintaining this consortium including initial regional geographic limitation, charter development with by-laws and procedures for adopting studies, and research infrastructure including a central website for study monitoring and central reliance institutional review board process. Conclusion Our model could be reproduced or adapted by other institutions to develop or strengthen other research collaboratives. Level of evidence Type of study: retrospective, IV.
AB - Background Multicenter clinical research studies in pediatric surgery have been largely limited to relatively small case-series and retrospective reviews because of the rarity of many of the diseases we treat and difficulty coordinating and executing multi-institutional studies. Creation of a collaborative research network can provide the needed patient population and infrastructure to perform high quality multi-institutional studies. Methods In 2013, eleven academic pediatric surgery centers within the United States formed a research consortium to develop and conduct multicenter clinical research projects to advance the practice of pediatric surgery. Results We present our process for creating, developing, and maintaining this consortium including initial regional geographic limitation, charter development with by-laws and procedures for adopting studies, and research infrastructure including a central website for study monitoring and central reliance institutional review board process. Conclusion Our model could be reproduced or adapted by other institutions to develop or strengthen other research collaboratives. Level of evidence Type of study: retrospective, IV.
KW - Clinical research
KW - Multi-institutional trials
KW - Research consortium
UR - http://www.scopus.com/inward/record.url?scp=85009282293&partnerID=8YFLogxK
U2 - 10.1016/j.jpedsurg.2016.11.042
DO - 10.1016/j.jpedsurg.2016.11.042
M3 - Article
C2 - 28081853
AN - SCOPUS:85009282293
SN - 0022-3468
VL - 52
SP - 1084
EP - 1088
JO - Journal of Pediatric Surgery
JF - Journal of Pediatric Surgery
IS - 7
ER -