Development and testing of hyperpolarized 13C MR calibrationless parallel imaging

Yesu Feng, Jeremy W. Gordon, Peter J. Shin, Cornelius Von Morze, Michael Lustig, Peder E.Z. Larson, Michael A. Ohliger, Lucas Carvajal, James Tropp, John M. Pauly, Daniel B. Vigneron

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Abstract

A calibrationless parallel imaging technique developed previously for 1H MRI was modified and tested for hyperpolarized 13C MRI for applications requiring large FOV and high spatial resolution. The technique was demonstrated with both retrospective and prospective under-sampled data acquired in phantom and in vivo rat studies. A 2-fold acceleration was achieved using a 2D symmetric EPI readout equipped with random blips on the phase encode dimension. Reconstructed images showed excellent qualitative agreement with fully sampled data. Further acceleration can be achieved using acquisition schemes that incorporate multi-dimensional under-sampling.

Original languageEnglish
Pages (from-to)1-7
Number of pages7
JournalJournal of Magnetic Resonance
Volume262
DOIs
StatePublished - Jan 2016
Externally publishedYes

Keywords

  • Carbon-13
  • Hyperpolarization
  • Parallel imaging

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    Feng, Y., Gordon, J. W., Shin, P. J., Von Morze, C., Lustig, M., Larson, P. E. Z., Ohliger, M. A., Carvajal, L., Tropp, J., Pauly, J. M., & Vigneron, D. B. (2016). Development and testing of hyperpolarized 13C MR calibrationless parallel imaging. Journal of Magnetic Resonance, 262, 1-7. https://doi.org/10.1016/j.jmr.2015.10.018