TY - JOUR
T1 - Developing role of magnetic resonance imaging in Crohn's disease
AU - Lin, Michael F.
AU - Narra, Vamsidhar
PY - 2008/3/1
Y1 - 2008/3/1
N2 - PURPOSE OF REVIEW: There is growing concern among the medical community that diagnostic radiation adds to the already increased risk of developing lymphoma that may be inherent in, or related to the treatment of, inflammatory bowel disease. This article describes recent progress in magnetic resonance enterography techniques, and examines the role of MRI in the evaluation of Crohn's disease. RECENT FINDINGS: Recent advancements in magnetic resonance technology and imaging protocol have made MRI of the small bowel feasible. With improved coils, breath-hold sequences and faster acquisition techniques, MRI capably depicts disease location, extent, and complications. Most of the current literature recognizes MRI as an excellent tool in characterizing transmural and extraluminal changes of Crohn's disease. SUMMARY: The lack of ionizing radiation is the main driving force for MRI of Crohn's disease. This advantage is magnified by the relatively young age of Crohn's disease patients. While intrinsic susceptibility to air and motion may limit its use in some patients, MRI shows promising potential as an alternative to computed tomography in monitoring disease progression or response to therapy.
AB - PURPOSE OF REVIEW: There is growing concern among the medical community that diagnostic radiation adds to the already increased risk of developing lymphoma that may be inherent in, or related to the treatment of, inflammatory bowel disease. This article describes recent progress in magnetic resonance enterography techniques, and examines the role of MRI in the evaluation of Crohn's disease. RECENT FINDINGS: Recent advancements in magnetic resonance technology and imaging protocol have made MRI of the small bowel feasible. With improved coils, breath-hold sequences and faster acquisition techniques, MRI capably depicts disease location, extent, and complications. Most of the current literature recognizes MRI as an excellent tool in characterizing transmural and extraluminal changes of Crohn's disease. SUMMARY: The lack of ionizing radiation is the main driving force for MRI of Crohn's disease. This advantage is magnified by the relatively young age of Crohn's disease patients. While intrinsic susceptibility to air and motion may limit its use in some patients, MRI shows promising potential as an alternative to computed tomography in monitoring disease progression or response to therapy.
KW - Crohn's disease
KW - MRI
KW - Magnetic resonance enterography
UR - http://www.scopus.com/inward/record.url?scp=40049103469&partnerID=8YFLogxK
U2 - 10.1097/MOG.0b013e3282f49b14
DO - 10.1097/MOG.0b013e3282f49b14
M3 - Review article
C2 - 18301262
AN - SCOPUS:40049103469
SN - 0267-1379
VL - 24
SP - 135
EP - 140
JO - Current Opinion in Gastroenterology
JF - Current Opinion in Gastroenterology
IS - 2
ER -