TY - JOUR
T1 - Determination of Atrazine in Water at Low-and Sub-Parts-per-Trillion Levels by Using Solid-Phase Extraction and Gas Chromatography/High-Resolution Mass Spectrometry
AU - Cai, Zongwei
AU - Ramanujam, V. M.Sadagopa
AU - Giblin, Daryl E.
AU - Spalding, Roy F.
AU - Gross, Michael L.
PY - 1993/1/1
Y1 - 1993/1/1
N2 - A capillary column gas chromatography/high-resolution mass spectrometry (GC/HRMS) method was developed to determine atrazine In water at low-and sub-parts-per-trillion (ppt) levels. The method fills a need when the detection limits of routine GC, GC/MS, and high-performance liquid chromatography (HPLC) are Inadequate for studies to evaluate transport and fate of herbicides In deep ground water systems. Atrazine and the added Internal standard [13C3]atrazlne were extracted from water samples by solid-phase extraction using a C18 bonded silica cartridge. A column chromatography procedure with Florisil was developed to reduce when necessary further Interferences In the sample extract. The analysis was performed by GC/HRMS with the mass spectrometer operated In the selected Ion monitoring (SIM) mode; mass profiles were acquired. The precision and accuracy of the method are 15% (relative standard deviation, n = 8) and >85%, respectively, for standard water samples containing atrazine at 1 ppt. The method, which gives detection limits of 200-500 parts-per-quadrillion (ppq), has been successfully used to analyze water samples containing atrazine at concentration levels of 1-500 ppt.
AB - A capillary column gas chromatography/high-resolution mass spectrometry (GC/HRMS) method was developed to determine atrazine In water at low-and sub-parts-per-trillion (ppt) levels. The method fills a need when the detection limits of routine GC, GC/MS, and high-performance liquid chromatography (HPLC) are Inadequate for studies to evaluate transport and fate of herbicides In deep ground water systems. Atrazine and the added Internal standard [13C3]atrazlne were extracted from water samples by solid-phase extraction using a C18 bonded silica cartridge. A column chromatography procedure with Florisil was developed to reduce when necessary further Interferences In the sample extract. The analysis was performed by GC/HRMS with the mass spectrometer operated In the selected Ion monitoring (SIM) mode; mass profiles were acquired. The precision and accuracy of the method are 15% (relative standard deviation, n = 8) and >85%, respectively, for standard water samples containing atrazine at 1 ppt. The method, which gives detection limits of 200-500 parts-per-quadrillion (ppq), has been successfully used to analyze water samples containing atrazine at concentration levels of 1-500 ppt.
UR - https://www.scopus.com/pages/publications/0003362869
U2 - 10.1021/ac00049a006
DO - 10.1021/ac00049a006
M3 - Article
AN - SCOPUS:0003362869
SN - 0003-2700
VL - 65
SP - 21
EP - 26
JO - Analytical Chemistry
JF - Analytical Chemistry
IS - 1
ER -