Detection of structural DNA variation from next generation sequencing data: A review of informatic approaches

Keyphrases

• Array-based 25%
• Balanced Translocation 25%
• Clinical Testing 25%
• Collective Group 25%
• Copy number Variation 50%
• Exome 25%
• Fluorescence in Situ Hybridization 25%
• Gene Panel 25%
• Informatics Approaches 100%
• Informetric Analysis 25%
• Insertion/deletion 50%
• Large Insertion 25%
• Map Data 25%
• Metagenomic Next-generation Sequencing (mNGS) 25%
• Next-generation Sequencing 75%
• Next-generation Sequencing Data 100%
• OR Genes 25%
• Reference Genome 25%
• Sanger Sequencing 25%
• Sequence Coverage 25%
• Sequence Data 25%
• Sequence Reads 25%
• Sequencing Depth 25%
• Single nucleotide Variant 50%
• Small Fraction 25%
• Structural DNA Variation 100%
• Structural Variation 75%
• Structural Variation Detection 25%
• Targeted Sequencing 25%
• Whole Genome Next Generation Sequencing 50%

Biochemistry, Genetics and Molecular Biology

• Copy-Number Variation 28%
• Dideoxynucleotide Sequencing 14%
• Exome 14%
• Fluorescence in Situ Hybridization 14%
• Indel 28%
• Next Generation Sequencing 100%
• Reference Genome 14%
• Single-Nucleotide Polymorphism 28%

Immunology and Microbiology

• Copy Number Variation 28%
• Dideoxynucleotide Sequencing 14%
• Exome 14%
• Fluorescence in Situ Hybridization 14%
• Indel Mutation 28%
• Next Generation Sequencing 100%
• Single Nucleotide Polymorphism 28%