Destroy to create: E3 ubiquitin ligases in neurogenesis

Judith Stegmüller, Azad Bonni

Research output: Contribution to journalReview article

18 Scopus citations


The ubiquitin proteasome system (UPS) has drawn tremendous attention in the field of neuroscience. In recent years, we have gained insights into UPS-dependent mechanisms in brain development and disease. Several interesting studies over the past two years have highlighted the role of distinct E3 ubiquitin ligases in neurogenesis. Here, we will review the major findings in these studies and discuss their implications.

Original languageEnglish
Article number38
JournalF1000 Biology Reports
Issue number1
StatePublished - May 24 2010

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