Abstract
The ubiquitin proteasome system (UPS) has drawn tremendous attention in the field of neuroscience. In recent years, we have gained insights into UPS-dependent mechanisms in brain development and disease. Several interesting studies over the past two years have highlighted the role of distinct E3 ubiquitin ligases in neurogenesis. Here, we will review the major findings in these studies and discuss their implications.
Original language | English |
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Article number | 38 |
Journal | F1000 Biology Reports |
Volume | 2 |
Issue number | 1 |
DOIs | |
State | Published - May 24 2010 |