Design and programming of the micromanipulator network to study single cardiac cell mechanics

  • D. A. Volzhaninov
  • , O. N. Lookin
  • , I. N. Antsygin
  • , A. D. Khokhlova

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Computer-controlled biomechanical experiments on single cells require high accuracy and synchronicity of signals and stability of experimental set-ups. In this paper, we propose a digital micromanipulator network consisting of two micromanipulators to study single cardiac cell mechanics. The micromanipulation system using Ethernet for this network has a large positioning range (20 mm), covering the experimental bath with the cells and nanometer movement resolution (5 nm) for precise experiments. The software for the micromanipulator network was developed in the LabVIEW to provide sufficient synchronicity of micromanipulator movement. The testing of seven consistent steps of two micromanipulators showed that movement was synchronous and maximum loss of synchrony of coordinates was 170 nm. We believe that studies on the changes in single cardiac cell length and force under various mechanical loads can be carried out using the developed network.

Original languageEnglish
Title of host publicationProceedings of the 2018 2nd International Conference on Computer Science and Artificial Intelligence, CSAI 2018 - 2018 the 10th International Conference on Information and Multimedia Technology, ICIMT 2018
PublisherAssociation for Computing Machinery
Pages455-458
Number of pages4
ISBN (Electronic)9781450366069
DOIs
StatePublished - Dec 8 2018
Event2nd International Conference on Computer Science and Artificial Intelligence, CSAI 2018 - Shenzhen, China
Duration: Dec 8 2018Dec 10 2018

Publication series

NameACM International Conference Proceeding Series

Conference

Conference2nd International Conference on Computer Science and Artificial Intelligence, CSAI 2018
Country/TerritoryChina
CityShenzhen
Period12/8/1812/10/18

Keywords

  • Biomechanics
  • Ethernet
  • LabVIEW
  • Micromanipulator network
  • Single cardiac cell

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