TY - JOUR
T1 - Describing the Weight-Reduced State
T2 - Physiology, Behavior, and Interventions
AU - Aronne, Louis J.
AU - Hall, Kevin D.
AU - M. Jakicic, John
AU - Leibel, Rudolph L.
AU - Lowe, Michael R.
AU - Rosenbaum, Michael
AU - Klein, Samuel
N1 - Publisher Copyright:
© 2021 The Obesity Society
PY - 2021/4
Y1 - 2021/4
N2 - Although many persons with obesity can lose weight by lifestyle (diet and physical activity) therapy, successful long-term weight loss is difficult to achieve, and most people who lose weight regain their lost weight over time. The neurohormonal, physiological, and behavioral factors that promote weight recidivism are unclear and complex. The National Institute of Diabetes and Digestive and Kidney Diseases convened a workshop in June 2019, titled “The Physiology of the Weight-Reduced State,” to explore the mechanisms and integrative physiology of adaptations in appetite, energy expenditure, and thermogenesis that occur in the weight-reduced state and that may oppose weight-loss maintenance. The proceedings from the first session of this workshop are presented here. Drs. Michael Rosenbaum, Kevin Hall, and Rudolph Leibel discussed the physiological factors that contribute to weight regain; Dr. Michael Lowe discussed the biobehavioral issues involved in weight-loss maintenance; Dr. John Jakicic discussed the influence of physical activity on long-term weight-loss maintenance; and Dr. Louis Aronne discussed the ability of drug therapy to maintain weight loss.
AB - Although many persons with obesity can lose weight by lifestyle (diet and physical activity) therapy, successful long-term weight loss is difficult to achieve, and most people who lose weight regain their lost weight over time. The neurohormonal, physiological, and behavioral factors that promote weight recidivism are unclear and complex. The National Institute of Diabetes and Digestive and Kidney Diseases convened a workshop in June 2019, titled “The Physiology of the Weight-Reduced State,” to explore the mechanisms and integrative physiology of adaptations in appetite, energy expenditure, and thermogenesis that occur in the weight-reduced state and that may oppose weight-loss maintenance. The proceedings from the first session of this workshop are presented here. Drs. Michael Rosenbaum, Kevin Hall, and Rudolph Leibel discussed the physiological factors that contribute to weight regain; Dr. Michael Lowe discussed the biobehavioral issues involved in weight-loss maintenance; Dr. John Jakicic discussed the influence of physical activity on long-term weight-loss maintenance; and Dr. Louis Aronne discussed the ability of drug therapy to maintain weight loss.
UR - http://www.scopus.com/inward/record.url?scp=85102922981&partnerID=8YFLogxK
U2 - 10.1002/oby.23086
DO - 10.1002/oby.23086
M3 - Article
C2 - 33759395
AN - SCOPUS:85102922981
SN - 1930-7381
VL - 29
SP - S9-S24
JO - Obesity
JF - Obesity
IS - S1
ER -