Dermatologic manifestations of cytotoxic therapy

Victor Huang; Milan Anadkat

doi:10.1111/j.1529-8019.2011.01432.x

Dermatologic manifestations of cytotoxic therapy

Victor Huang
, Milan Anadkat

Research output: Contribution to journal › Review article › peer-review

23 Scopus citations

Abstract

Cytotoxic agents represent the oldest class of chemotherapy drugs. These agents interrupt the replication of rapidly dividing malignant and nonmalignant cells by interfering with DNA replication. Resultant toxicity commonly affects the bone marrow, skin, and intestinal epithelium. In addition, there exist specific dermatologic reaction patterns that may appear. The present review highlights the most common specific and nonspecific dermatologic adverse effects seen with cytotoxic chemotherapeutic agents.

Original language	English
Pages (from-to)	401-410
Number of pages	10
Journal	Dermatologic Therapy
Volume	24
Issue number	4
DOIs	https://doi.org/10.1111/j.1529-8019.2011.01432.x
State	Published - Jul 1 2011

Keywords

adverse effects
cutaneous
cytotoxic

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10.1111/j.1529-8019.2011.01432.x

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abstract = "Cytotoxic agents represent the oldest class of chemotherapy drugs. These agents interrupt the replication of rapidly dividing malignant and nonmalignant cells by interfering with DNA replication. Resultant toxicity commonly affects the bone marrow, skin, and intestinal epithelium. In addition, there exist specific dermatologic reaction patterns that may appear. The present review highlights the most common specific and nonspecific dermatologic adverse effects seen with cytotoxic chemotherapeutic agents.",

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AU - Huang, Victor

AU - Anadkat, Milan

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N2 - Cytotoxic agents represent the oldest class of chemotherapy drugs. These agents interrupt the replication of rapidly dividing malignant and nonmalignant cells by interfering with DNA replication. Resultant toxicity commonly affects the bone marrow, skin, and intestinal epithelium. In addition, there exist specific dermatologic reaction patterns that may appear. The present review highlights the most common specific and nonspecific dermatologic adverse effects seen with cytotoxic chemotherapeutic agents.

AB - Cytotoxic agents represent the oldest class of chemotherapy drugs. These agents interrupt the replication of rapidly dividing malignant and nonmalignant cells by interfering with DNA replication. Resultant toxicity commonly affects the bone marrow, skin, and intestinal epithelium. In addition, there exist specific dermatologic reaction patterns that may appear. The present review highlights the most common specific and nonspecific dermatologic adverse effects seen with cytotoxic chemotherapeutic agents.

KW - adverse effects

KW - cutaneous

KW - cytotoxic

UR - https://www.scopus.com/pages/publications/80052764928

U2 - 10.1111/j.1529-8019.2011.01432.x

DO - 10.1111/j.1529-8019.2011.01432.x

M3 - Review article

C2 - 21910798

AN - SCOPUS:80052764928

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SP - 401

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JO - Dermatologic Therapy

JF - Dermatologic Therapy

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Dermatologic manifestations of cytotoxic therapy

Abstract

Keywords

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