TY - JOUR
T1 - Depressive symptoms in women seeking surgery for pelvic organ prolapse
AU - Ghetti, Chiara
AU - Lowder, Jerry L.
AU - Ellison, Rennique
AU - Krohn, M. A.
AU - Moalli, Pamela
N1 - Funding Information:
This research was funded in part by NIH/NICHD 2K12 HD43441-06 (Dr. Ghetti) and the 2007 American Urogynecologic Society Foundation–Astellas Research Award (Dr. Lowder). C.Ghetti(*).J.L.Lowder.R.Ellison.M.A.Krohn. P. Moalli Department of Obstetrics, Gynecology, and Reproductive Sciences, Division of Urogynecology, Magee Womens Hospital, University of Pittsburgh, 300 Halket Street, Pittsburgh, PA 15213, USA e-mail: [email protected]
PY - 2010/7
Y1 - 2010/7
N2 - Introduction and hypothesis: To compare depressive symptoms in women with and without prolapse and evaluate impact on quality of life. Methods: This is a secondary analysis of a case-control study assessing the effect of prolapse on body image. Cases had prolapse and sought surgery (Pelvic Organ Prolapse Quantification stage ≥2). Controls had stage ≥1. Subjects completed the Pelvic Floor Impact Questionnaire (PFIQ), Pelvic Floor Distress Inventory, and the Patient Health Questionnaire-9 (PHQ-9) at baseline. Cases completed measures 6 months post-operatively. We report: (1) the comparison of cases and controls at baseline and (2) comparison of baseline and post-operative scores in cases. Results: Baseline questionnaires were completed by 75 cases and 65 controls; 57 cases completed post-operative measures. Cases were 5-fold more likely than controls to have depressive symptoms. Cases with depressive symptoms had higher PFIQ scores than cases without symptoms. PHQ-9 scores improved post-operatively. Conclusions: Depressive symptoms are common in women with prolapse and a decrease following surgical treatment.
AB - Introduction and hypothesis: To compare depressive symptoms in women with and without prolapse and evaluate impact on quality of life. Methods: This is a secondary analysis of a case-control study assessing the effect of prolapse on body image. Cases had prolapse and sought surgery (Pelvic Organ Prolapse Quantification stage ≥2). Controls had stage ≥1. Subjects completed the Pelvic Floor Impact Questionnaire (PFIQ), Pelvic Floor Distress Inventory, and the Patient Health Questionnaire-9 (PHQ-9) at baseline. Cases completed measures 6 months post-operatively. We report: (1) the comparison of cases and controls at baseline and (2) comparison of baseline and post-operative scores in cases. Results: Baseline questionnaires were completed by 75 cases and 65 controls; 57 cases completed post-operative measures. Cases were 5-fold more likely than controls to have depressive symptoms. Cases with depressive symptoms had higher PFIQ scores than cases without symptoms. PHQ-9 scores improved post-operatively. Conclusions: Depressive symptoms are common in women with prolapse and a decrease following surgical treatment.
KW - Depressive symptoms
KW - Pelvic organ prolapse
KW - Quality of life
KW - Surgery
UR - http://www.scopus.com/inward/record.url?scp=77953016553&partnerID=8YFLogxK
U2 - 10.1007/s00192-010-1106-4
DO - 10.1007/s00192-010-1106-4
M3 - Article
C2 - 20333505
AN - SCOPUS:77953016553
SN - 0937-3462
VL - 21
SP - 855
EP - 860
JO - International Urogynecology Journal
JF - International Urogynecology Journal
IS - 7
ER -