TY - JOUR
T1 - Depressive symptoms and glycemic control in youth with type 2 diabetes participating in the TODAY clinical trial
AU - For the TODAY Study Group
AU - Van Buren, Dorothy J.
AU - Wilfley, Denise E.
AU - Marcus, Marsha D.
AU - Anderson, Barbara
AU - Abramson, Natalie Walders
AU - Berkowitz, Robert
AU - Ievers-Landis, Carolyn
AU - Trief, Paula
AU - Yasuda, Patrice
AU - Hirst, Kathryn
N1 - Funding Information:
This work was completed with funding from NIDDK and the NIH Office of the Director through grants U01-DK61212 , U01-DK61230 , U01-DK61239 , U01-DK61242 , and U01-DK61254 ; the National Center for Research Resources (NCRR) General Clinical Research Centers Program through grants M01-RR00036 (Washington University School of Medicine); and from the NCRR Clinical and Translational Science Awards through grants UL1-RR024992 (Washington University in St. Louis). The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. The NIDDK project office was involved in all aspects of the study, including: design and conduct; collection, management, analysis, and interpretation of the data; review and approval of the manuscript; and decision to submit the manuscript for publication.
Funding Information:
TODAY, a collaborative, multi-center randomized clinical trial (15 clinical centers and a data coordinating center), was funded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) of the National Institutes of Health. The study design, objectives and primary outcomes have been previously reported [5] . An External Evaluation Committee convened by the NIDDK approved the protocol as did the individual Institutional Review Boards. All participants provided informed consent; minor children confirmed assent per local guidelines. Enrollment was May 2004 - February 2009 (total n = 699). Eligible participants were 10–17 years of age, with type 2 diabetes < 2 years and a BMI ≥ 85th percentile at diagnosis. Participants were followed for a minimum of two years.
Publisher Copyright:
© 2017 Elsevier B.V.
PY - 2018/1
Y1 - 2018/1
N2 - The relationship between depressive symptoms and glycemic control in youth with type 2 diabetes was assessed at baseline (n = 682), 6, and/or 24 months (n = 576). Neither baseline nor persistence of depressive symptoms was significantly associated with maintenance of glycemic control. Nevertheless, depressive symptoms were common, suggesting the importance of repeated screening.
AB - The relationship between depressive symptoms and glycemic control in youth with type 2 diabetes was assessed at baseline (n = 682), 6, and/or 24 months (n = 576). Neither baseline nor persistence of depressive symptoms was significantly associated with maintenance of glycemic control. Nevertheless, depressive symptoms were common, suggesting the importance of repeated screening.
KW - Adolescent
KW - Depressive symptoms
KW - Type 2 diabetes
UR - http://www.scopus.com/inward/record.url?scp=85034849232&partnerID=8YFLogxK
U2 - 10.1016/j.diabres.2017.11.008
DO - 10.1016/j.diabres.2017.11.008
M3 - Article
C2 - 29146120
AN - SCOPUS:85034849232
SN - 0168-8227
VL - 135
SP - 85
EP - 87
JO - Diabetes Research and Clinical Practice
JF - Diabetes Research and Clinical Practice
ER -