This article reviews recent empirical literature on the prevalence, correlates, assessment, and treatment of preschool-onset internalizing disorders. Major advances in the acceptance and recognition of both preschool-onset depression and anxiety have occurred over the past decade. This work has been greatly enhanced by the discovery of genetic, neural, and physiologic indicators, which further validate these constellations of symptoms in young children. Despite this growth in research, much work still needs to be done to further elucidate the cause, risk, treatment, and protective factors for preschool-onset internalizing disorders.

Original languageEnglish
Pages (from-to)503-522
Number of pages20
JournalChild and Adolescent Psychiatric Clinics of North America
Issue number3
StatePublished - Jul 2017


  • Early onset
  • Mental disorder
  • Preschool anxiety
  • Preschool depression
  • Review


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