Abstract

Dendritic cells (DCs) represent a unique collection of innate immune cells present throughout the body as distinct subpopulations generally sharing the functions of pathogen recognition, cytokine production, and antigen presentation. A large body of work in recent years has examined DC functions during infection with Listeria monocytogenes (Lm), particularly in the murine model. Here, I review several aspects of DC biology in this model, with particular emphasis on the role DCs play in the establishment of a productive Lm infection and the role of DCs as cytokine producers and antigen-presenting cells in this system.

Original languageEnglish
Title of host publicationAdvances in Immunology
PublisherAcademic Press Inc.
Pages33-49
Number of pages17
DOIs
StatePublished - 2012

Publication series

NameAdvances in Immunology
Volume113
ISSN (Print)0065-2776
ISSN (Electronic)1557-8445

Keywords

  • Dendritic cells
  • Infection
  • Listeria monocytogenes
  • Periarteriolar lymphoid sheath
  • Spleen

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