Defining terms commonly used in sarcopenia research: a glossary proposed by the Global Leadership in Sarcopenia (GLIS) Steering Committee

Peggy M. Cawthon, Marjolein Visser, Hidenori Arai, José A. Ávila-Funes, Rocco Barazzoni, Shalender Bhasin, Ellen Binder, Olivier Bruyère, Tommy Cederholm, Liang Kung Chen, Cyrus Cooper, Gustavo Duque, Roger A. Fielding, Jack Guralnik, Douglas P. Kiel, Ben Kirk, Francesco Landi, Avan A. Sayer, Stephan Von Haehling, Jean WooAlfonso J. Cruz-Jentoft

Research output: Contribution to journalArticlepeer-review

45 Scopus citations


Methods: The aim of this paper is to define terms commonly related to sarcopenia to enable standardization of these terms in research and clinical settings. The Global Leadership Initiative in Sarcopenia (GLIS) aims to bring together leading investigators in sarcopenia research to develop a single definition that can be utilized worldwide; work on a global definition of sarcopenia is ongoing. The first step of GLIS is to develop the common terminology, or a glossary, that will facilitate agreement on a global definition of sarcopenia as well as interpretation of clinical and research findings. Results: Several terms that are commonly used in sarcopenia research are defined, including self-reported measures of function and ability; objective physical performance tests; and measures related to muscle function and size. Conclusion: As new methods and technologies are developed, these definitions may be expanded or refined over time. Our goal is to promote this common language to describe sarcopenia and its components in clinical and research settings in order to increase clinical awareness and research interest in this important condition. We hope that the use of common terminology in sarcopenia research will increase understanding of the concept and improve communication around this important age-related condition.

Original languageEnglish
Pages (from-to)1239-1244
Number of pages6
JournalEuropean Geriatric Medicine
Issue number6
StatePublished - Dec 2022


  • GLIS
  • Sarcopenia
  • Standardization
  • Terminology


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