Defining stage-specific activity of potent new inhibitors of cryptosporidium parvum growth in vitro

Keyphrases

• Specific Activity 100%
• Mechanism of Action 100%
• New Inhibitors 100%
• Cryptosporidium Parvum 100%
• Growth in Vitro 100%
• Cidal Activity 100%
• Phosphatidylinositol 4-phosphate 5-kinase (PIP5K) 66%
• Phenylalanine 66%
• Life Cycle Stages 66%
• Cryptosporidiosis 66%
• TRNA Synthetase 66%
• Static Activity 66%
• Gene Expression 33%
• Monoclonal Antibody 33%
• Small Molecules 33%
• FDA-approved Drugs 33%
• Daughter Cells 33%
• In Vitro Assay 33%
• Potent Inhibitor 33%
• Highly Active 33%
• Long-term Culture 33%
• In Vivo Applications 33%
• Piperazine 33%
• Time-to-treatment 33%
• Immunocompromised Patients 33%
• Activity-dependent 33%
• Nitazoxanide 33%
• Intestinal Stem Cells 33%
• Egress 33%
• In Vivo Efficacy 33%
• Kinase Inhibitor 33%
• Epithelial Monolayer 33%
• Culture System 33%
• Developing World 33%
• Enteric Pathogens 33%
• In Vitro Parameters 33%
• Active Compounds 33%
• Cryptosporidium 33%
• Immunocompetent Individual 33%
• Life Cycle Development 33%
• Parvum 33%
• Sexual Stage 33%
• Stage Development 33%
• Antibody Expression 33%
• Immunocompromised Adults 33%
• Compound Classes 33%
• Under 1 Year of Age 33%
• Long-term Cultivation 33%
• Cryptosporidium Hominis 33%
• Activity Timing 33%

Pharmacology, Toxicology and Pharmaceutical Science

• Cryptosporidium parvum 100%
• Hexachlorophene 100%
• Cryptosporidiosis 50%
• Phosphatidylinositol Kinase 50%
• Phenylalanine Transfer RNA Ligase 50%
• Monoclonal Antibody 25%
• Infectious Agent 25%
• Piperazine 25%
• Nitazoxanide 25%
• Phosphotransferase Inhibitor 25%
• Immunocompromised Patient 25%
• Efficacy Study 25%
• Cryptosporidium hominis 25%
• Cryptosporidium 25%

Immunology and Microbiology

• Life Cycle 100%
• Cryptosporidium parvum 100%
• Transfer RNA 40%
• Phenylalanine 40%
• Gene Expression 20%
• Monoclonal Antibody 20%
• Infectious Agent 20%
• Immunocompromised Patient 20%
• Developmental Stage 20%
• Intestinal Stem Cell 20%
• Daughter Cell 20%
• Cryptosporidium 20%
• Cryptosporidium hominis 20%