Defining cellular complexity in human autosomal dominant polycystic kidney disease by multimodal single cell analysis

Keyphrases

• Autosomal Dominant Polycystic Kidney Disease (ADPKD) 100%
• Multimodal Single-cell 100%
• Single-cell Analysis 100%
• Cellular Complexity 100%
• Collecting Duct Cells 40%
• GPRC5A 40%
• Single-cell multi-omics 40%
• Cyst 20%
• Healthy Individuals 20%
• Fibroblasts 20%
• End-stage Renal Disease 20%
• Genetic Causes 20%
• Therapeutic Approaches 20%
• Renal Tubular Epithelial Cells 20%
• Diagnostic Approach 20%
• NF-B 20%
• Kidney Disease Progression 20%
• Epigenome 20%
• Transcription Factor Binding Sites 20%
• Human Kidney 20%
• Single-cell Transcriptomics 20%
• Single nucleus 20%
• Retinoic Acid Receptor 20%
• Cellular Heterogeneity 20%
• Failed Repair 20%
• Transcriptomic Signature 20%
• Kidney Cyst 20%
• Multi-omics Analysis 20%
• Distal Enhancer 20%
• Profibrotic Signaling Pathways 20%

Biochemistry, Genetics and Molecular Biology

• Autosomal Dominant Polycystic Kidney 100%
• Single-Cell Analysis 100%
• Enhancer Region 20%
• Genetics 20%
• Normal Human 20%
• Transcription Factors 20%
• Epigenome 20%
• Transcriptomics 20%
• Retinoic Acid Receptor 20%
• CREB 20%
• Fibroblast 20%
• Transcriptome 20%

Medicine and Dentistry

• Polycystic Kidney Disease 100%
• Collecting Duct 40%
• Disease Exacerbation 20%
• End Stage Renal Disease 20%
• Transcription Factors 20%
• Enhancer Region 20%
• Transcriptomics 20%
• Cell Signaling Pathway 20%
• Transcriptome 20%
• Retinoic Acid Receptor 20%
• Renal Cyst 20%
• Fibroblast 20%