Defining and Modulating ‘BRCAness’

Medicine and Dentistry

• BRCA1 100%
• PARP Inhibitor 100%
• Neoplasm 50%
• Genomic Instability 50%
• DNA Repair 50%
• Lethality 50%
• Kinase 50%
• Proteus Syndrome 50%
• BRCA2 50%
• Homologous Recombination 50%
• Recombination Repair 50%
• DNA Damage Checkpoint 50%

Keyphrases

• BRCAness 100%
• Replication Fork Stability 50%
• PARP Inhibitor (PARPi) 33%
• Tumor 16%
• DNA Damage 16%
• Vulnerability 16%
• Small Molecule Inhibitors 16%
• Breast Cancer Susceptibility Gene 1 (BRCA1) 16%
• BRCA1, BRCA2 16%
• Regulatory Mechanism 16%
• Protection Mechanism 16%
• Checkpoint Kinase 1 (CHK1) 16%
• Multiple Cancers 16%
• DNA Damage Checkpoint 16%
• Synthetic Lethality 16%
• Genomic Instability 16%
• DNA Repair Pathways 16%
• Translational Potential 16%
• BRCA2 16%
• Checkpoint Molecules 16%
• Homologous Recombination Repair 16%
• Protection Regulations 16%
• Error-prone DNA Repair 16%
• Largest Subset 16%
• BRCA Deficiency 16%

Biochemistry, Genetics and Molecular Biology

• BRCA1 100%
• Poly ADP Ribose Polymerase 100%
• DNA Repair 50%
• Homologous Recombination 50%
• Genome Instability 50%
• Small Molecule 50%
• DNA Damage Checkpoint 50%
• Recombination Repair 50%
• BRCA2 50%