Deficiency of XLF and PAXX prevents DNA double-strand break repair by non-homologous end joining in lymphocytes

Keyphrases

• Lymphocytes 100%
• Non-homologous End Joining 100%
• DNA Double-strand Break Repair 100%
• XRCC4 100%
• V(D)J Recombination 15%
• DNA Ligase IV 10%
• Ionizing Radiation 10%
• Redundant Function 10%
• Double-strand Break Repair 10%
• Combined Deficiency 5%
• C-terminal Region 5%
• Repair Factors 5%
• Immunodeficiency 5%
• All-phase 5%
• Repair Pathway 5%
• Antigen Receptor Loci 5%
• Factor Deficiency 5%
• End Joining 5%
• Ku80 5%
• Murine Lymphocytes 5%
• Non-homologous End Joining Repair 5%

Immunology and Microbiology

• Paralogy 100%
• DNA End Joining Repair 100%
• Lymphocyte 100%
• Double-Strand DNA Break 100%
• V(D)J Recombination 25%
• Carboxy Terminal Sequence 8%
• Cell Cycle 8%
• Antigen 8%
• Immunodeficiency 8%