Decreased phytohemagglutinin receptor sites in chronic lymphocytic leukemia

TY - JOUR

T1 - Decreased phytohemagglutinin receptor sites in chronic lymphocytic leukemia

AU - Kornfeld, Stuart

N1 - Funding Information: cytes also have less sialic acid on their surfaces than do normal lymphocytes although the cellular distribution on a percentage basis is the same. These experiments demonstrate that the cell surface of chronic lymphocytic leukemic lymphocytes differs considerably from the cell surface of normal lymphocytes. The decreased number of phytohemagglutinin receptor sites is probably just one reflection of the altered cell surface. The findir@ that the ABH blood group antigens have markedly decreased or even absent reactivity in chronic lymphocytic leukemic lymphocytes compared to normal lymphocytes is consistent with this proposal. This research was supported in part by grants from the U.S. Public Health Service (HE-ooozz and ROI CA-08759) and the American Cancer Society (PRA31).

PY - 1969/12/30

Y1 - 1969/12/30

UR - http://www.scopus.com/inward/record.url?scp=0014696504&partnerID=8YFLogxK

U2 - 10.1016/0304-4165(69)90409-7

DO - 10.1016/0304-4165(69)90409-7

M3 - Article

C2 - 5368257

AN - SCOPUS:0014696504

SN - 0304-4165

VL - 192

SP - 542

EP - 545

JO - BBA - General Subjects

JF - BBA - General Subjects

IS - 3

ER -