Decreased cortical thickness & osteopenia in children with diabetes mellitus

J. V. Santiago; W. H. McAlister; S. K. Ratzan; Y. Bussman; M. W. Haymond; G. Shackelford; V. V. Weldon

doi:10.1210/jcem-45-4-845

Decreased cortical thickness & osteopenia in children with diabetes mellitus

J. V. Santiago, W. H. McAlister, S. K. Ratzan, Y. Bussman, M. W. Haymond, G. Shackelford, V. V. Weldon

Section of Pediatric Radiology

Research output: Contribution to journal › Article › peer-review

122 Scopus citations

Abstract

A recent study using the photon absorption technique has revealed a high frequency of significant bone loss in diabetic adults regardless of age or duration of diabetes. In this study 107 diabetic children age 4-18 were studied using cortical bone thickness and skeletal maturation as indicators of bone development. Overall, 25% of all diabetic children had cortical thickness values below the five percent limit for normal children. This was more common in boys than girls and was unrelated to duration of diabetes. A modest increase in delayed skeletal maturation did not account for the cortical thinning and osteopenia observed. The cause of the osteopenia of diabetic children remains an enigma.

Original language	English
Pages (from-to)	845-848
Number of pages	4
Journal	Journal of Clinical Endocrinology and Metabolism
Volume	45
Issue number	4
DOIs	https://doi.org/10.1210/jcem-45-4-845
State	Published - Oct 1977

Access to Document

10.1210/jcem-45-4-845

Cite this

@article{42971812389d4f13975d473096a3ebff,

title = "Decreased cortical thickness & osteopenia in children with diabetes mellitus",

abstract = "A recent study using the photon absorption technique has revealed a high frequency of significant bone loss in diabetic adults regardless of age or duration of diabetes. In this study 107 diabetic children age 4-18 were studied using cortical bone thickness and skeletal maturation as indicators of bone development. Overall, 25% of all diabetic children had cortical thickness values below the five percent limit for normal children. This was more common in boys than girls and was unrelated to duration of diabetes. A modest increase in delayed skeletal maturation did not account for the cortical thinning and osteopenia observed. The cause of the osteopenia of diabetic children remains an enigma.",

author = "Santiago, {J. V.} and McAlister, {W. H.} and Ratzan, {S. K.} and Y. Bussman and Haymond, {M. W.} and G. Shackelford and Weldon, {V. V.}",

year = "1977",

month = oct,

doi = "10.1210/jcem-45-4-845",

language = "English",

volume = "45",

pages = "845--848",

journal = "Journal of Clinical Endocrinology and Metabolism",

issn = "0021-972X",

number = "4",

}

TY - JOUR

T1 - Decreased cortical thickness & osteopenia in children with diabetes mellitus

AU - Santiago, J. V.

AU - McAlister, W. H.

AU - Ratzan, S. K.

AU - Bussman, Y.

AU - Haymond, M. W.

AU - Shackelford, G.

AU - Weldon, V. V.

PY - 1977/10

Y1 - 1977/10

N2 - A recent study using the photon absorption technique has revealed a high frequency of significant bone loss in diabetic adults regardless of age or duration of diabetes. In this study 107 diabetic children age 4-18 were studied using cortical bone thickness and skeletal maturation as indicators of bone development. Overall, 25% of all diabetic children had cortical thickness values below the five percent limit for normal children. This was more common in boys than girls and was unrelated to duration of diabetes. A modest increase in delayed skeletal maturation did not account for the cortical thinning and osteopenia observed. The cause of the osteopenia of diabetic children remains an enigma.

AB - A recent study using the photon absorption technique has revealed a high frequency of significant bone loss in diabetic adults regardless of age or duration of diabetes. In this study 107 diabetic children age 4-18 were studied using cortical bone thickness and skeletal maturation as indicators of bone development. Overall, 25% of all diabetic children had cortical thickness values below the five percent limit for normal children. This was more common in boys than girls and was unrelated to duration of diabetes. A modest increase in delayed skeletal maturation did not account for the cortical thinning and osteopenia observed. The cause of the osteopenia of diabetic children remains an enigma.

UR - http://www.scopus.com/inward/record.url?scp=0017689502&partnerID=8YFLogxK

U2 - 10.1210/jcem-45-4-845

DO - 10.1210/jcem-45-4-845

M3 - Article

C2 - 914988

AN - SCOPUS:0017689502

SN - 0021-972X

VL - 45

SP - 845

EP - 848

JO - Journal of Clinical Endocrinology and Metabolism

JF - Journal of Clinical Endocrinology and Metabolism

IS - 4

ER -

Decreased cortical thickness & osteopenia in children with diabetes mellitus

Abstract

Access to Document

Other files and links

Fingerprint

Cite this