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Decoupling dedifferentiation and G
2
/M arrest in kidney fibrosis
Benjamin D. Humphreys
Department of Medicine
Center of Regenerative Medicine
Roy and Diana Vagelos Division of Biology & Biomedical Sciences (DBBS)
Division of Nephrology
DBBS - Computational and Systems Biology
DBBS - Developmental, Regenerative and Stem Cell Biology
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/M arrest in kidney fibrosis'. Together they form a unique fingerprint.
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Medicine & Life Sciences
Cyclin G1
100%
Fibrosis
48%
Kidney
34%
Chronic Renal Insufficiency
29%
Cyclin G2
29%
Disease Progression
26%
Cell Cycle Checkpoints
15%
Knockout Mice
14%
Therapeutics
5%