Deadly Splicing: Bax Becomes Almighty

Hyungjin Kim, James J.D. Hsieh, Emily H.Y. Cheng

Research output: Contribution to journalShort surveypeer-review

6 Scopus citations

Abstract

Activation of Bax and Bak by BH3-only molecules triggers mitochondrial apoptosis. In a recent issue of Molecular Cell, Fu et al. (2009) identify a constitutively active isoform of Bax, Baxβ, whose activity is tightly controlled by the ubiquitin-proteasome system.

Original languageEnglish
Pages (from-to)145-146
Number of pages2
JournalMolecular cell
Volume33
Issue number2
DOIs
StatePublished - Jan 30 2009

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