De Novo Membranoproliferative Glomerulonephritis III in a renal transplant patient: Case report and review of the literature

Anuja Java, Joseph P. Gaut, Daniel C. Brennan

Research output: Contribution to journalReview articlepeer-review

Abstract

Idiopathic membranoproliferative glomerulonephritis (MPGN) is a rare cause of renal failure with a cumulative incidence of 0.3% of all ESRD and 4% of all primary glomerulonephritis for types I and II. Membranoproliferative glomerulonephritis type III is more uncommon and idiopathic de novo MPGN III in a renal transplant patient has not been reported. We present the case of a 57-year old white female patient with a diagnosis of lithium toxicity as cause of end stage renal disease (ESRD) who developed MPGN III in her allograft 6 years after a renal transplant. Despite treatment, she progressed to ESRD within four and a half years from the time of diagnosis.

Original languageEnglish
Pages (from-to)e58-e61
JournalTransplant International
Volume25
Issue number5
DOIs
StatePublished - May 2012

Keywords

  • glomerulonephritis
  • immunosuppression
  • kidney
  • membranoproliferative
  • recurrence
  • transplant

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