Abstract
A database of curated genomic variants with clinically supported drug therapies and other oncological annotations is described. The accompanying web portal provides a search engine with two modes: one that allows users to query gene, cancer type, variant type or position for druggable mutations, and another to search for and to visualize, on three-dimensional protein structures, putative druggable sites that cluster with known druggable mutations.
Original language | English |
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Pages (from-to) | 4315-4317 |
Number of pages | 3 |
Journal | Bioinformatics |
Volume | 34 |
Issue number | 24 |
DOIs | |
State | Published - Dec 15 2018 |