Dancing with the Stars: Phenolic Glycolipids Partners with Macrophages

Micah D. Dunlap, Shabaana A. Khader

Research output: Contribution to journalShort survey

1 Scopus citations

Abstract

How Mycobacterium leprae infection causes demyelination to mediate leprosy pathogenesis has been a long-standing question. In a recent Cell paper, Madigan et al. (2017) use a zebrafish model of M. leprae infection to show that infected macrophages patrol axons to trigger mitochondrial damage and induce demyelination of nerve cells. How Mycobacterium leprae infection causes demyelination to mediate leprosy pathogenesis has been a long-standing question. In a recent Cell paper, Madigan et al. (2017) use a zebrafish model of M. leprae infection to show that infected macrophages patrol axons to trigger mitochondrial damage and induce demyelination of nerve cells.

Original languageEnglish
Pages (from-to)249-251
Number of pages3
JournalCell Host and Microbe
Volume22
Issue number3
DOIs
StatePublished - Sep 13 2017

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