Dancing with the Stars: Phenolic Glycolipids Partners with Macrophages

Micah D. Dunlap; Shabaana A. Khader

doi:10.1016/j.chom.2017.08.016

Dancing with the Stars: Phenolic Glycolipids Partners with Macrophages

Micah D. Dunlap, Shabaana A. Khader

Research output: Contribution to journal › Short survey › peer-review

1 Scopus citations

Abstract

How Mycobacterium leprae infection causes demyelination to mediate leprosy pathogenesis has been a long-standing question. In a recent Cell paper, Madigan et al. (2017) use a zebrafish model of M. leprae infection to show that infected macrophages patrol axons to trigger mitochondrial damage and induce demyelination of nerve cells. How Mycobacterium leprae infection causes demyelination to mediate leprosy pathogenesis has been a long-standing question. In a recent Cell paper, Madigan et al. (2017) use a zebrafish model of M. leprae infection to show that infected macrophages patrol axons to trigger mitochondrial damage and induce demyelination of nerve cells.

Original language	English
Pages (from-to)	249-251
Number of pages	3
Journal	Cell Host and Microbe
Volume	22
Issue number	3
DOIs	https://doi.org/10.1016/j.chom.2017.08.016
State	Published - Sep 13 2017

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abstract = "How Mycobacterium leprae infection causes demyelination to mediate leprosy pathogenesis has been a long-standing question. In a recent Cell paper, Madigan et al. (2017) use a zebrafish model of M. leprae infection to show that infected macrophages patrol axons to trigger mitochondrial damage and induce demyelination of nerve cells. How Mycobacterium leprae infection causes demyelination to mediate leprosy pathogenesis has been a long-standing question. In a recent Cell paper, Madigan et al. (2017) use a zebrafish model of M. leprae infection to show that infected macrophages patrol axons to trigger mitochondrial damage and induce demyelination of nerve cells.",

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