Cytomegalovirus-associated acute retinal necrosis syndrome

B. E. Silverstien, D. Conrad, T. P. Margolis, I. G. Wong

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PURPOSE: To describe a case of acute retinal necrosis syndrome in which a polymerase chain reaction-based assay provided evidence for cytomegalovirus as the causative agent of the syndrome. METHODS: Polymerase chain reaction- based assays were used to analyze a vitreous aspirate from a 70-year-old man with acute retinal necrosis syndrome. The specimen was tested for cytomegalovirus, varicella-zoster virus, and herpes simplex virus type 1 and type 2. RESULTS: The polymerase chain reaction assay for cytomegalovirus was positive, and polymerase chain reaction assays for varicella-zoster virus and herpes simplex virus type 1 and type 2 were negative. CONCLUSION: Cytomegalovirus may be a causative agent of acute retinal necrosis syndrome.

Original languageEnglish
Pages (from-to)257-258
Number of pages2
JournalAmerican journal of ophthalmology
Issue number2
StatePublished - Feb 20 1997
Externally publishedYes

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    Silverstien, B. E., Conrad, D., Margolis, T. P., & Wong, I. G. (1997). Cytomegalovirus-associated acute retinal necrosis syndrome. American journal of ophthalmology, 123(2), 257-258.