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Cytolytic nanoparticles attenuate HIV-1 infectivity
Joshua L. Hood
, Andrew P. Jallouk
, Nancy Campbell
,
Lee Ratner
, Samuel A. Wickline
Bursky Center for Human Immunology & Immunotherapy Programs (CHiiPs)
Roy and Diana Vagelos Division of Biology & Biomedical Sciences (DBBS)
Institute of Clinical and Translational Sciences (ICTS)
Siteman Cancer Center
Section of Molecular Oncology & Developmental Therapeutics
Division of Oncology
DBBS - Molecular Microbiology and Microbial Pathogenesis
DBBS - Molecular Genetics and Genomics
DBBS - Cancer Biology
Research output
:
Contribution to journal
›
Article
›
peer-review
109
Scopus citations
Overview
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Keyphrases
Human Immunodeficiency Virus Type 1 (HIV-1)
100%
Nanoparticles
100%
Infectivity
100%
Cytolytic
100%
Melittin
100%
C-X-C Chemokine Receptor Type 4 (CXCR4)
42%
C-C Chemokine Receptor Type 5 (CCR5)
28%
Reporter Cells
28%
Cell Viability
21%
IC50
21%
CCR5-tropic
21%
TZM-bl Cells
21%
Positive Control
14%
CD41
14%
Soluble CD4
14%
Highly Effective
7%
Cytotoxicity
7%
Luciferase
7%
Viral Strains
7%
Enveloped Virus
7%
Tropics
7%
50% Inhibitory Concentration
7%
Initial Infection
7%
Vaginal Cells
7%
Vaginal Epithelial Cells
7%
Low-speed Centrifugation
7%
Virucide
7%
HIV-1 Promoter
7%
Immunology and Microbiology
Human Immunodeficiency Virus 1
100%
Melittin
100%
Infection
100%
CCR5
50%
CXCR4
42%
IC50
28%
Cell Viability
21%
CD4
14%
IC90
14%
Promoter Region
7%
Centrifugation
7%
Cytotoxicity
7%
Virus Strain
7%
Virucide
7%
Virus
7%
Peptides
7%
Pharmacology, Toxicology and Pharmaceutical Science
Infection
100%
Nanoparticle
100%
HIV
100%
Melittin
100%
IC50
28%
Cell Viability
21%
Antivirus Agent
14%
Luciferase
7%
Virus Strain
7%
Cytotoxicity
7%
Agricultural and Biological Sciences
Human Immunodeficiency Virus
100%
Nanoparticle
100%
Melittin
100%
CXCR4
42%
Cell Viability
21%
CD4
14%
Centrifugation
7%
Epithelial Cells
7%
Inhibitory Concentration 50
7%
Luciferase
7%
Cytotoxicity
7%
Veterinary Science and Veterinary Medicine
CCR5
100%
CD4
28%
Infectious Disease
14%