Cytokine signaling in 2002: New surprises in the Jak/Stat pathway

John J. OShea; Massimo Gadina; Robert D. Schreiber

doi:10.1016/S0092-8674(02)00701-8

Cytokine signaling in 2002: New surprises in the Jak/Stat pathway

John J. OShea
, Massimo Gadina
, Robert D. Schreiber

Research output: Contribution to journal › Review article › peer-review

1034 Scopus citations

Abstract

The importance of Jak-Stat pathway signaling in regulating cytokine-dependent gene expression and cellular development/survival is well established. Nevertheless, advances continue to be made in defining Jak-Stat pathway effects on different cellular processes and in different organisms. This review focuses on recent advances in the field and highlights some of the most active areas of Jak-Stat pathway research.

Original language	English
Pages (from-to)	S121-S131
Journal	Cell
Volume	109
Issue number	2 SUPPL. 1
DOIs	https://doi.org/10.1016/S0092-8674(02)00701-8
State	Published - 2002

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10.1016/S0092-8674(02)00701-8

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title = "Cytokine signaling in 2002: New surprises in the Jak/Stat pathway",

abstract = "The importance of Jak-Stat pathway signaling in regulating cytokine-dependent gene expression and cellular development/survival is well established. Nevertheless, advances continue to be made in defining Jak-Stat pathway effects on different cellular processes and in different organisms. This review focuses on recent advances in the field and highlights some of the most active areas of Jak-Stat pathway research.",

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AU - Gadina, Massimo

AU - Schreiber, Robert D.

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Y1 - 2002

N2 - The importance of Jak-Stat pathway signaling in regulating cytokine-dependent gene expression and cellular development/survival is well established. Nevertheless, advances continue to be made in defining Jak-Stat pathway effects on different cellular processes and in different organisms. This review focuses on recent advances in the field and highlights some of the most active areas of Jak-Stat pathway research.

AB - The importance of Jak-Stat pathway signaling in regulating cytokine-dependent gene expression and cellular development/survival is well established. Nevertheless, advances continue to be made in defining Jak-Stat pathway effects on different cellular processes and in different organisms. This review focuses on recent advances in the field and highlights some of the most active areas of Jak-Stat pathway research.

UR - https://www.scopus.com/pages/publications/0036233585

U2 - 10.1016/S0092-8674(02)00701-8

DO - 10.1016/S0092-8674(02)00701-8

M3 - Review article

C2 - 11983158

AN - SCOPUS:0036233585

SN - 0092-8674

VL - 109

SP - S121-S131

JO - Cell

JF - Cell

IS - 2 SUPPL. 1

ER -

Cytokine signaling in 2002: New surprises in the Jak/Stat pathway

Abstract

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