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Cytochrome P450 polymorphisms are associated with reduced warfarin dose
Bradley D. Freeman
, Barbara A. Zehnbauer
, Sean McGrath
, Ingrid Borecki
, Timothy G. Buchman
Institute of Clinical and Translational Sciences (ICTS)
Section of Acute and Critical Care Surgery
Research output
:
Contribution to journal
›
Article
›
peer-review
78
Scopus citations
Overview
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Keyphrases
Warfarin Dose
100%
CYP2C9
100%
Cytochrome P450 Polymorphisms
100%
CYP2A6
56%
Genotype
18%
Warfarin
18%
Polymorphism
12%
Cytochrome P450 (CYP450)
12%
Warfarin Therapy
12%
Metabolism
6%
Patient Demographics
6%
Dose-response
6%
Polymerase Chain Reaction Amplification
6%
T-test
6%
Warfarin Sensitivity
6%
Inter-patient Variability
6%
Genotype Frequency
6%
2 Polymorphism
6%
Polymorphic Alleles
6%
Pharmacology, Toxicology and Pharmaceutical Science
Warfarin
100%
Cytochrome P450
100%
CYP2C9
100%
CYP2A6
75%
CYP2C9*3
33%
Biochemistry, Genetics and Molecular Biology
CYP2C9
100%
Cytochrome P450
100%
CYP2A6
75%
Genotyping
33%
CYP2C9*3
33%
Wild Type
16%
Allele
16%
Metabolic Pathway
8%
Dose Response
8%
Polymerase Chain Reaction
8%
Neuroscience
Cytochrome P450
100%
Warfarin
100%
Cytochrome P450 2C9
100%
CYP2A6
56%
Metabolic Pathway
6%
Polymerase Chain Reaction
6%