Cystosarcoma phyllodes of the prostate. A pathological and immunohistochemical study

C. Manivel, B. V. Shenoy, M. R. Wick, L. P. Dehner

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42 Scopus citations


We treated two patients who had lesions in the prostate with histologic features similar to those of cystosarcoma phyllodes of the breast. In one case, the stroma progressed to a clearly sarcomatous appearance, whereas the other tumor had a cellular stroma that was mitotically inactive. This element was immunoreactive for vimentin and desmin in both cases but was negative for epithelial markers. In contrast, the epithelial component was immunoreactive for prostate-specific antigen and epithelial membrane antigen. Following surgical resection, both patients were well two and three years later, without local recurrence or distant metastasis. The histogenesis of these tumors is unknown.

Original languageEnglish
Pages (from-to)534-538
Number of pages5
JournalArchives of Pathology and Laboratory Medicine
Issue number6
StatePublished - Jan 1 1986
Externally publishedYes

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